Cell atlas - NEBL - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

NEBL

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	NEBL
Gene description	Nebulette
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SCLC-21H, SK-BR-3, SH-SY5Y)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, SK-BR-3, SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	NEBL
Synonyms
Description	Nebulette (HGNC Symbol)
Entrez gene summary	This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Chromosome	10
Cytoband	p12.31
Chromosome location (bp)	20779973 - 21174187
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000078114 (version 83.38)
Entrez gene	10529
UniProt	O76041 (UniProt - Evidence at protein level)
neXtProt	NX_O76041
Antibodypedia	NEBL antibodies

PROTEIN BROWSER

NEBL-001	NEBL-003	NEBL-004	NEBL-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NEBL-001 ENSP00000489562 ENST00000473616		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.7 kDa	No	0
NEBL-003 ENSP00000393896 ENST00000417816	O76041 [Direct mapping] Nebulette Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0005515 [protein binding] GO:0005523 [tropomyosin binding] GO:0008092 [cytoskeletal protein binding] GO:0008270 [zinc ion binding] GO:0008307 [structural constituent of muscle] GO:0030018 [Z disc] GO:0031005 [filamin binding] GO:0031674 [I band] GO:0051015 [actin filament binding] GO:0070062 [extracellular exosome] GO:0071691 [cardiac muscle thin filament assembly] Show all	270 aa 31.2 kDa	No	0
NEBL-004 ENSP00000366326 ENST00000377122	O76041 [Direct mapping] Nebulette Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0005515 [protein binding] GO:0005523 [tropomyosin binding] GO:0008092 [cytoskeletal protein binding] GO:0008307 [structural constituent of muscle] GO:0030018 [Z disc] GO:0031005 [filamin binding] GO:0031674 [I band] GO:0051015 [actin filament binding] GO:0070062 [extracellular exosome] GO:0071691 [cardiac muscle thin filament assembly] Show all	1014 aa 116.5 kDa	No	0
NEBL-009 ENSP00000396512 ENST00000434381	Q5JUU7 [Direct mapping] Nebulette Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		117 aa 13.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.