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SDF4

GENERAL INFORMATION

Gene name

 SDF4

Gene description

 Stromal cell derived factor 4

Protein class

 Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in several tissues, most abundant in testis and the intestine.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA011249 , CAB015227
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SDF4 (HGNC Symbol)

Synonyms

 Cab45

Description

 Stromal cell derived factor 4 (HGNC Symbol)

Entrez gene summary

 This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011]

Chromosome

 1

Cytoband

 p36.33

Chromosome location (bp)

 1216908 - 1232031

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000078808 (version 83.38)

Entrez gene

 51150

UniProt

 Q9BRK5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BRK5

Antibodypedia

 SDF4 antibodies

PROTEIN BROWSER
SDF4-001
SDF4-006
SDF4-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SDF4-001
ENSP00000353094
ENST00000360001
Q9BRK5 [Direct mapping]
45 kDa calcium-binding protein
A0A024R084 [Target identity:100%; Query identity:100%]
Stromal cell derived factor 4, isoform CRA_c
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   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005770 [late endosome]
GO:0005794 [Golgi apparatus]
GO:0005796 [Golgi lumen]
GO:0005886 [plasma membrane]
GO:0009650 [UV protection]
GO:0016020 [membrane]
GO:0017156 [calcium ion-dependent exocytosis]
GO:0021549 [cerebellum development]
GO:0032059 [bleb]
GO:0042802 [identical protein binding]
GO:0045444 [fat cell differentiation]
GO:0045471 [response to ethanol]
GO:0070062 [extracellular exosome]
GO:0070625 [zymogen granule exocytosis]
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 362 aa
41.8 kDa 		Yes 0
SDF4-006
ENSP00000384207
ENST00000403997
H0Y3T6 [Direct mapping]
45 kDa calcium-binding protein
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005509 [calcium ion binding]
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 243 aa
28 kDa 		No 0
SDF4-007
ENSP00000263741
ENST00000263741
Q9BRK5 [Direct mapping]
45 kDa calcium-binding protein
A0A024R0A9 [Target identity:100%; Query identity:100%]
Stromal cell derived factor 4, isoform CRA_b
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005770 [late endosome]
GO:0005794 [Golgi apparatus]
GO:0005796 [Golgi lumen]
GO:0005886 [plasma membrane]
GO:0009650 [UV protection]
GO:0016020 [membrane]
GO:0017156 [calcium ion-dependent exocytosis]
GO:0021549 [cerebellum development]
GO:0032059 [bleb]
GO:0042802 [identical protein binding]
GO:0045444 [fat cell differentiation]
GO:0045471 [response to ethanol]
GO:0070062 [extracellular exosome]
GO:0070625 [zymogen granule exocytosis]
Show all
 348 aa
39.6 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.