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UBE2D4

GENERAL INFORMATION

Gene name

 UBE2D4

Gene description

 Ubiquitin-conjugating enzyme E2D 4 (putative)

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear membranous expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 1 antibody.
HPA003920
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Appendix
N/A
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 UBE2D4 (HGNC Symbol)

Synonyms

 HBUCE1

Description

 Ubiquitin-conjugating enzyme E2D 4 (putative) (HGNC Symbol)

Entrez gene summary

Chromosome

 7

Cytoband

 p13

Chromosome location (bp)

 43926438 - 43956136

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000078967 (version 83.38)

Entrez gene

 51619

UniProt

 Q9Y2X8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2X8

Antibodypedia

 UBE2D4 antibodies

PROTEIN BROWSER
UBE2D4-001
UBE2D4-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
UBE2D4-001
ENSP00000222402
ENST00000222402
Q9Y2X8 [Direct mapping]
Ubiquitin-conjugating enzyme E2 D4
A0A024RA90 [Target identity:100%; Query identity:100%]
Ubiquitin-conjugating enzyme E2D 4 (Putative), isoform CRA_e
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Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0016567 [protein ubiquitination]
GO:0035519 [protein K29-linked ubiquitination]
GO:0044314 [protein K27-linked ubiquitination]
GO:0061631 [ubiquitin conjugating enzyme activity]
GO:0070534 [protein K63-linked ubiquitination]
GO:0070936 [protein K48-linked ubiquitination]
GO:0070979 [protein K11-linked ubiquitination]
GO:0085020 [protein K6-linked ubiquitination]
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 147 aa
16.6 kDa 		No 0
UBE2D4-009
ENSP00000397406
ENST00000446008
C9J9H9 [Direct mapping]
Ubiquitin-conjugating enzyme E2 D4
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Predicted intracellular proteins
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GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016874 [ligase activity]
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 122 aa
13.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.