Cell atlas - FKBP7 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

FKBP7

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Endoplasmic reticulum

Human cell
	Endoplasmic Reticulum

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	FKBP7
Gene description	FK506 binding protein 7
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the endoplasmic reticulum.
RNA cell category	Cell line enhanced (ASC TERT1)
Protein evidence	Evidence at protein level
Main location	Localized to the Endoplasmic reticulum (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA008707
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (ASC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the endoplasmic reticulum.

Main location

Endoplasmic reticulum (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA008707	A-431	Endoplasmic reticulum
	HPA008707	U-2 OS	Endoplasmic reticulum
	HPA008707	U-251 MG	Endoplasmic reticulum

GENE INFORMATION
Gene name	FKBP7 (HGNC Symbol)
Synonyms	FKBP23
Description	FK506 binding protein 7 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q31.2
Chromosome location (bp)	178463664 - 178478600
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000079150 (version 83.38)
Entrez gene	51661
UniProt	Q9Y680 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y680
Antibodypedia	FKBP7 antibodies

PROTEIN BROWSER

FKBP7-001	FKBP7-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FKBP7-001 ENSP00000413152 ENST00000424785	Q9Y680 [Direct mapping] Peptidyl-prolyl cis-trans isomerase FKBP7 Show all	Enzymes ENZYME proteins Isomerase MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005528 [FK506 binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005788 [endoplasmic reticulum lumen] GO:0005789 [endoplasmic reticulum membrane] GO:0006457 [protein folding] GO:0061077 [chaperone-mediated protein folding] Show all	222 aa 25.8 kDa	Yes	0
FKBP7-008 ENSP00000415486 ENST00000434643	Q9Y680 [Direct mapping] Peptidyl-prolyl cis-trans isomerase FKBP7 Show all	Enzymes ENZYME proteins Isomerase MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005528 [FK506 binding] GO:0005737 [cytoplasm] GO:0005788 [endoplasmic reticulum lumen] GO:0005789 [endoplasmic reticulum membrane] GO:0006457 [protein folding] GO:0061077 [chaperone-mediated protein folding] Show all	221 aa 25.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.