Cell atlas - RDH8 - The Human Protein Atlas

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RDH8

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RDH8
Gene description	Retinol dehydrogenase 8 (all-trans)
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RDH8 (HGNC Symbol)
Synonyms	PRRDH, SDR28C2
Description	Retinol dehydrogenase 8 (all-trans) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	10013249 - 10022279
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000080511 (version 83.38)
Entrez gene	50700
UniProt
neXtProt
Antibodypedia	RDH8 antibodies

PROTEIN BROWSER

RDH8-001	RDH8-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RDH8-001 ENSP00000466058 ENST00000591589	K7ELF7 [Direct mapping] Retinol dehydrogenase 8 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004303 [estradiol 17-beta-dehydrogenase activity] GO:0004745 [retinol dehydrogenase activity] GO:0005737 [cytoplasm] GO:0006703 [estrogen biosynthetic process] GO:0007601 [visual perception] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0042572 [retinol metabolic process] GO:0055114 [oxidation-reduction process] Show all	331 aa 35.8 kDa	No	0
RDH8-002 ENSP00000465773 ENST00000587782	K7EKT5 [Direct mapping] Retinol dehydrogenase 8 Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		79 aa 8.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.