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MEF2C
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    TISSUE

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  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

MEF2C

Gene description

Myocyte enhancer factor 2C

Protein class

Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

27
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression, most abundant in CNS, skeletal muscle, endothelial and lymphoid cells.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 3 antibodies.
HPA005533 , CAB068196 , CAB068197
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

MEF2C

Synonyms

Description

Myocyte enhancer factor 2C (HGNC Symbol)

Entrez gene summary

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]

Chromosome

5

Cytoband

q14.3

Chromosome location (bp)

88717117 - 88904257

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000081189 (version 83.38)

Entrez gene

4208

UniProt

Q06413 (UniProt - Evidence at protein level)

neXtProt

NX_Q06413

Antibodypedia

MEF2C antibodies

PROTEIN BROWSER

«
MEF2C-001
MEF2C-003
MEF2C-004
MEF2C-005
MEF2C-007
MEF2C-009
MEF2C-010
MEF2C-012
MEF2C-013
MEF2C-014
MEF2C-015
MEF2C-016
MEF2C-017
MEF2C-019
MEF2C-022
MEF2C-023
MEF2C-024
MEF2C-025
MEF2C-026
MEF2C-027
MEF2C-028
MEF2C-029
MEF2C-031
MEF2C-032
MEF2C-034
MEF2C-035
MEF2C-036
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MEF2C-001
ENSP00000421925
ENST00000504921
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL7 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_b
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Protein evidence (Kim et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
473 aa
51.2 kDa
No 0
MEF2C-003
ENSP00000396219
ENST00000437473
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL7 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_b
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
473 aa
51.2 kDa
No 0
MEF2C-004
ENSP00000389610
ENST00000424173
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
463 aa
50.2 kDa
No 0
MEF2C-005
ENSP00000340874
ENST00000340208
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0000987 [core promoter proximal region sequence-specific DNA binding]
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001205 [transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014898 [cardiac muscle hypertrophy in response to stress]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030224 [monocyte differentiation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0042826 [histone deacetylase binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043565 [sequence-specific DNA binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045165 [cell fate commitment]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0048703 [embryonic viscerocranium morphogenesis]
GO:0048704 [embryonic skeletal system morphogenesis]
GO:0050680 [negative regulation of epithelial cell proliferation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060021 [palate development]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060297 [regulation of sarcomere organization]
GO:0060536 [cartilage morphogenesis]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0071837 [HMG box domain binding]
GO:0071864 [positive regulation of cell proliferation in bone marrow]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
483 aa
52.3 kDa
No 0
MEF2C-007
ENSP00000486554
ENST00000629612
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL6 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_a
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
465 aa
50.3 kDa
No 0
MEF2C-009
ENSP00000486490
ENST00000627659
A0A0D9SFD0 [Direct mapping]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_e; Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
431 aa
46.9 kDa
No 0
MEF2C-010
ENSP00000427163
ENST00000502983
D6RCM6 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
129 aa
14.9 kDa
No 0
MEF2C-012
ENSP00000423826
ENST00000513252
D6RC63 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
242 aa
26.6 kDa
No 0
MEF2C-013
ENSP00000426465
ENST00000503075
D6RG14 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
87 aa
10.3 kDa
No 0
MEF2C-014
ENSP00000426442
ENST00000508610
D6RG21 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
126 aa
14.6 kDa
No 0
MEF2C-015
ENSP00000424331
ENST00000507984
D6RB91 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
120 aa
14.1 kDa
No 0
MEF2C-016
ENSP00000423656
ENST00000506716
D6R942 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
227 aa
25 kDa
No 0
MEF2C-017
ENSP00000427309
ENST00000509373
D6RJ95 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
28 aa
3.5 kDa
No 0
MEF2C-019
ENSP00000487437
ENST00000503554
A0A0D9SGF3 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
103 aa
10.5 kDa
No 0
MEF2C-022
ENSP00000422390
ENST00000510942
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0046983 [protein dimerization activity]
Show all
433 aa
47 kDa
No 0
MEF2C-023
ENSP00000424606
ENST00000514015
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
441 aa
47.9 kDa
No 0
MEF2C-024
ENSP00000423597
ENST00000508569
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
A0A024RAL6 [Target identity:100%; Query identity:100%]
MADS box transcription enhancer factor 2, polypeptide C (Myocyte enhancer factor 2C), isoform CRA_a
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
465 aa
50.3 kDa
No 0
MEF2C-025
ENSP00000425636
ENST00000506554
D6RJG6 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046983 [protein dimerization activity]
Show all
399 aa
43.1 kDa
No 0
MEF2C-026
ENSP00000487430
ENST00000625674
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
463 aa
50.2 kDa
No 0
MEF2C-027
ENSP00000485972
ENST00000631026
A0A0D9SET2 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
205 aa
22.9 kDa
No 0
MEF2C-028
ENSP00000426665
ENST00000514028
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
441 aa
47.9 kDa
No 0
MEF2C-029
ENSP00000487538
ENST00000625585
A0A0D9SGI5 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
471 aa
51.1 kDa
No 0
MEF2C-031
ENSP00000487184
ENST00000626391
D8L7E9 [Direct mapping]
Myocyte enhancer factor 2c; Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
393 aa
42.5 kDa
No 0
MEF2C-032
ENSP00000487311
ENST00000628656
Q06413 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Transcription factors
   alpha-Helices exposed by beta-structures
Disease related genes
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000165 [MAPK cascade]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0000983 [transcription factor activity, RNA polymerase II core promoter sequence-specific]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001568 [blood vessel development]
GO:0001649 [osteoblast differentiation]
GO:0001764 [neuron migration]
GO:0001782 [B cell homeostasis]
GO:0001947 [heart looping]
GO:0001958 [endochondral ossification]
GO:0001974 [blood vessel remodeling]
GO:0002062 [chondrocyte differentiation]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002467 [germinal center formation]
GO:0002634 [regulation of germinal center formation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0002756 [MyD88-independent toll-like receptor signaling pathway]
GO:0003138 [primary heart field specification]
GO:0003139 [secondary heart field specification]
GO:0003151 [outflow tract morphogenesis]
GO:0003185 [sinoatrial valve morphogenesis]
GO:0003211 [cardiac ventricle formation]
GO:0003677 [DNA binding]
GO:0003680 [AT DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006915 [apoptotic process]
GO:0006959 [humoral immune response]
GO:0007399 [nervous system development]
GO:0007507 [heart development]
GO:0007517 [muscle organ development]
GO:0007519 [skeletal muscle tissue development]
GO:0007521 [muscle cell fate determination]
GO:0007611 [learning or memory]
GO:0009615 [response to virus]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0010694 [positive regulation of alkaline phosphatase activity]
GO:0014033 [neural crest cell differentiation]
GO:0014902 [myotube differentiation]
GO:0016607 [nuclear speck]
GO:0030182 [neuron differentiation]
GO:0030220 [platelet formation]
GO:0030279 [negative regulation of ossification]
GO:0030318 [melanocyte differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0030890 [positive regulation of B cell proliferation]
GO:0033613 [activating transcription factor binding]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034138 [toll-like receptor 3 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034146 [toll-like receptor 5 signaling pathway]
GO:0034162 [toll-like receptor 9 signaling pathway]
GO:0034166 [toll-like receptor 10 signaling pathway]
GO:0035198 [miRNA binding]
GO:0035666 [TRIF-dependent toll-like receptor signaling pathway]
GO:0035690 [cellular response to drug]
GO:0035984 [cellular response to trichostatin A]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042100 [B cell proliferation]
GO:0042692 [muscle cell differentiation]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043234 [protein complex]
GO:0043523 [regulation of neuron apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0044212 [transcription regulatory region DNA binding]
GO:0045087 [innate immune response]
GO:0045652 [regulation of megakaryocyte differentiation]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048666 [neuron development]
GO:0048667 [cell morphogenesis involved in neuron differentiation]
GO:0050853 [B cell receptor signaling pathway]
GO:0051145 [smooth muscle cell differentiation]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051403 [stress-activated MAPK cascade]
GO:0051963 [regulation of synapse assembly]
GO:0051966 [regulation of synaptic transmission, glutamatergic]
GO:0055012 [ventricular cardiac muscle cell differentiation]
GO:0060025 [regulation of synaptic activity]
GO:0060045 [positive regulation of cardiac muscle cell proliferation]
GO:0060079 [excitatory postsynaptic potential]
GO:0060998 [regulation of dendritic spine development]
GO:0061333 [renal tubule morphogenesis]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071277 [cellular response to calcium ion]
GO:0071374 [cellular response to parathyroid hormone stimulus]
GO:0071498 [cellular response to fluid shear stress]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
GO:0072102 [glomerulus morphogenesis]
GO:0072160 [nephron tubule epithelial cell differentiation]
GO:0090073 [positive regulation of protein homodimerization activity]
GO:2000111 [positive regulation of macrophage apoptotic process]
GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
GO:2000727 [positive regulation of cardiac muscle cell differentiation]
GO:2000987 [positive regulation of behavioral fear response]
GO:2001013 [epithelial cell proliferation involved in renal tubule morphogenesis]
GO:2001016 [positive regulation of skeletal muscle cell differentiation]
Show all
417 aa
44.9 kDa
No 0
MEF2C-034
ENSP00000427286
ENST00000502831
D6RJA7 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
194 aa
21.8 kDa
No 0
MEF2C-035
ENSP00000486932
ENST00000627717
A0A0D9SFV9 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
183 aa
18.9 kDa
No 0
MEF2C-036
ENSP00000487157
ENST00000627170
A0A0D9SG58 [Direct mapping]
Myocyte-specific enhancer factor 2C
Show all
Predicted intracellular proteins
Show all
151 aa
15.9 kDa
No 0

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The Human Protein Atlas project is funded
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