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STK17B

GENERAL INFORMATION

Gene name

 STK17B

Gene description

 Serine/threonine kinase 17b

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (bone marrow)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues, most abundant in lymphoid tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA034858
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (bone marrow)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 STK17B (HGNC Symbol)

Synonyms

 DRAK2

Description

 Serine/threonine kinase 17b (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q32.3

Chromosome location (bp)

 196133566 - 196176503

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000081320 (version 83.38)

Entrez gene

 9262

UniProt

 O94768 (UniProt - Evidence at protein level)

neXtProt

 NX_O94768

Antibodypedia

 STK17B antibodies

PROTEIN BROWSER
STK17B-001
STK17B-002
STK17B-003
STK17B-004
STK17B-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STK17B-001
ENSP00000263955
ENST00000263955
O94768 [Direct mapping]
Serine/threonine-protein kinase 17B
Q53QE7 [Target identity:100%; Query identity:100%]
Putative uncharacterized protein STK17B; Serine/threonine kinase 17b (Apoptosis-inducing); cDNA, FLJ93309, Homo sapiens serine/threonine kinase 17b (apoptosis-inducing) (STK17B), mRNA
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0006915 [apoptotic process]
GO:0012501 [programmed cell death]
GO:0015629 [actin cytoskeleton]
GO:0035556 [intracellular signal transduction]
GO:0046777 [protein autophosphorylation]
GO:2000271 [positive regulation of fibroblast apoptotic process]
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 372 aa
42.3 kDa 		No 1
STK17B-002
ENSP00000386853
ENST00000409228
O94768 [Direct mapping]
Serine/threonine-protein kinase 17B
Q53QE7 [Target identity:100%; Query identity:100%]
Putative uncharacterized protein STK17B; Serine/threonine kinase 17b (Apoptosis-inducing); cDNA, FLJ93309, Homo sapiens serine/threonine kinase 17b (apoptosis-inducing) (STK17B), mRNA
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0035556 [intracellular signal transduction]
GO:0046777 [protein autophosphorylation]
GO:2000271 [positive regulation of fibroblast apoptotic process]
Show all
 372 aa
42.3 kDa 		No 1
STK17B-003
ENSP00000399755
ENST00000420683
C9JZJ1 [Direct mapping]
Serine/threonine-protein kinase 17B
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
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 67 aa
7.8 kDa 		No 0
STK17B-004
ENSP00000413289
ENST00000449152
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 6 aa
0.9 kDa 		No 0
STK17B-005
ENSP00000475843
ENST00000606789
U3KQF8 [Direct mapping]
Serine/threonine-protein kinase 17B
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 69 aa
8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.