Expression of JMJD4 in cancer - Summary - The Human Protein Atlas

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JMJD4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	JMJD4
Gene description	Jumonji domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA027260 , HPA052861
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027260	HPA052861

GENE INFORMATION
Gene name	JMJD4 (HGNC Symbol)
Synonyms	FLJ12517
Description	Jumonji domain containing 4 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q42.13
Chromosome location (bp)	227730425 - 227735411
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000081692 (version 83.38)
Entrez gene	65094
UniProt	Q9H9V9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H9V9
Antibodypedia	JMJD4 antibodies

PROTEIN BROWSER

JMJD4-001	JMJD4-002	JMJD4-006	JMJD4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
JMJD4-001 ENSP00000355720 ENST00000366758	Q9H9V9 [Direct mapping] JmjC domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	463 aa 52.5 kDa	No	0
JMJD4-002 ENSP00000387830 ENST00000438896	Q9H9V9 [Direct mapping] JmjC domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	447 aa 50.5 kDa	No	0
JMJD4-006 ENSP00000477669 ENST00000620518	A0A087WT84 [Direct mapping] JmjC domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		417 aa 47.4 kDa	No	0
JMJD4-201 ENSP00000484088 ENST00000615711	Q9H9V9 [Direct mapping] JmjC domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	463 aa 52.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.