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EPB41L3

GENERAL INFORMATION

Gene name

 EPB41L3

Gene description

 Erythrocyte membrane protein band 4.1-like 3

Protein class

 Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 24
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues, often with a membranous pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, Splice and/or transcript discrepancy exists.

Reliability score

 Approved based on 1 antibody.
HPA028605
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 EPB41L3 (HGNC Symbol)

Synonyms

 4.1B, DAL1, KIAA0987

Description

 Erythrocyte membrane protein band 4.1-like 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 18

Cytoband

 p11.31

Chromosome location (bp)

 5392381 - 5630700

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000082397 (version 83.38)

Entrez gene

 23136

UniProt

 Q9Y2J2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2J2

Antibodypedia

 EPB41L3 antibodies

PROTEIN BROWSER
«
EPB41L3-001
EPB41L3-002
EPB41L3-004
EPB41L3-007
EPB41L3-009
EPB41L3-010
EPB41L3-011
EPB41L3-012
EPB41L3-013
EPB41L3-014
EPB41L3-015
EPB41L3-017
EPB41L3-019
EPB41L3-020
EPB41L3-021
EPB41L3-022
EPB41L3-023
EPB41L3-024
EPB41L3-025
EPB41L3-032
EPB41L3-033
EPB41L3-201
EPB41L3-202
EPB41L3-203
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EPB41L3-001
ENSP00000343158
ENST00000341928
Q9Y2J2 [Direct mapping]
Band 4.1-like protein 3 Band 4.1-like protein 3, N-terminally processed
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0002175 [protein localization to paranode region of axon]
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006915 [apoptotic process]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0008092 [cytoskeletal protein binding]
GO:0008150 [biological_process]
GO:0008360 [regulation of cell shape]
GO:0019898 [extrinsic component of membrane]
GO:0030673 [axolemma]
GO:0030865 [cortical cytoskeleton organization]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030913 [paranodal junction assembly]
GO:0033270 [paranode region of axon]
GO:0043217 [myelin maintenance]
GO:0044224 [juxtaparanode region of axon]
GO:0048812 [neuron projection morphogenesis]
GO:0071205 [protein localization to juxtaparanode region of axon]
GO:0072659 [protein localization to plasma membrane]
GO:0097481 [neuronal postsynaptic density]
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 1087 aa
120.7 kDa 		No 1
EPB41L3-002
ENSP00000488626
ENST00000545076
A8K968 [Target identity:100%; Query identity:100%]
cDNA FLJ77757
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0008092 [cytoskeletal protein binding]
GO:0019898 [extrinsic component of membrane]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 756 aa
84.7 kDa 		No 0
EPB41L3-004
ENSP00000442091
ENST00000540638
Q9Y2J2 [Direct mapping]
Band 4.1-like protein 3 Band 4.1-like protein 3, N-terminally processed
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0002175 [protein localization to paranode region of axon]
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006915 [apoptotic process]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0008092 [cytoskeletal protein binding]
GO:0008150 [biological_process]
GO:0008360 [regulation of cell shape]
GO:0019898 [extrinsic component of membrane]
GO:0030673 [axolemma]
GO:0030865 [cortical cytoskeleton organization]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030913 [paranodal junction assembly]
GO:0033270 [paranode region of axon]
GO:0043217 [myelin maintenance]
GO:0044224 [juxtaparanode region of axon]
GO:0048812 [neuron projection morphogenesis]
GO:0071205 [protein localization to juxtaparanode region of axon]
GO:0072659 [protein localization to plasma membrane]
Show all
 865 aa
96.5 kDa 		No 0
EPB41L3-007
ENSP00000464020
ENST00000580308
J3QR33 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 127 aa
13.8 kDa 		No 0
EPB41L3-009
ENSP00000464533
ENST00000578503
J3QS55 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 162 aa
18 kDa 		No 0
EPB41L3-010
ENSP00000462338
ENST00000582703
J3KS70 [Direct mapping]
Band 4.1-like protein 3
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 91 aa
9.9 kDa 		No 0
EPB41L3-011
ENSP00000463122
ENST00000580989
J3QKK4 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 125 aa
13.6 kDa 		No 0
EPB41L3-012
ENSP00000462692
ENST00000584651
J3QS55 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 162 aa
18 kDa 		No 0
EPB41L3-013
ENSP00000463289
ENST00000585142
J3QKY2 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 113 aa
12.3 kDa 		No 0
EPB41L3-014
ENSP00000461937
ENST00000581833
J3KRD1 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 117 aa
12.7 kDa 		No 0
EPB41L3-015
ENSP00000464148
ENST00000584015
J3QR33 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 127 aa
13.8 kDa 		No 0
EPB41L3-017
ENSP00000463707
ENST00000582592
J3QLU5 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 96 aa
10.2 kDa 		No 0
EPB41L3-019
ENSP00000462783
ENST00000584670
J3KT37 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 147 aa
16.8 kDa 		No 0
EPB41L3-020
ENSP00000487786
ENST00000581292
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0008092 [cytoskeletal protein binding]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 184 aa
20.2 kDa 		No 0
EPB41L3-021
ENSP00000487915
ENST00000581387
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0008092 [cytoskeletal protein binding]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 194 aa
21.8 kDa 		No 0
EPB41L3-022
ENSP00000488037
ENST00000580647
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0008092 [cytoskeletal protein binding]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 190 aa
21.3 kDa 		No 0
EPB41L3-023
ENSP00000488647
ENST00000578524
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0008092 [cytoskeletal protein binding]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 325 aa
35.4 kDa 		No 0
EPB41L3-024
ENSP00000488095
ENST00000579271
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0008092 [cytoskeletal protein binding]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 197 aa
21.9 kDa 		No 0
EPB41L3-025
ENSP00000487780
ENST00000580316
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005856 [cytoskeleton]
GO:0008092 [cytoskeletal protein binding]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 188 aa
20.9 kDa 		No 0
EPB41L3-032
ENSP00000464570
ENST00000579951
J3QS83 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
Show all
 110 aa
11.7 kDa 		No 0
EPB41L3-033
ENSP00000464336
ENST00000580179
J3QRQ6 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 79 aa
8.5 kDa 		No 0
EPB41L3-201
ENSP00000341138
ENST00000342933
A0A0A0MRA8 [Direct mapping]
Band 4.1-like protein 3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0008092 [cytoskeletal protein binding]
GO:0019898 [extrinsic component of membrane]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 918 aa
102.3 kDa 		No 0
EPB41L3-202
ENSP00000382981
ENST00000400111
B2RB02 [Direct mapping]
Band 4.1-like protein 3; cDNA, FLJ95236, highly similar to Homo sapiens differentially expressed in adenocarcinoma of the lung, mRNA
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0008092 [cytoskeletal protein binding]
GO:0019898 [extrinsic component of membrane]
GO:0030866 [cortical actin cytoskeleton organization]
Show all
 503 aa
57.7 kDa 		No 0
EPB41L3-203
ENSP00000441174
ENST00000544123
Q9Y2J2 [Direct mapping]
Band 4.1-like protein 3 Band 4.1-like protein 3, N-terminally processed
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001558 [regulation of cell growth]
GO:0002175 [protein localization to paranode region of axon]
GO:0003779 [actin binding]
GO:0005198 [structural molecule activity]
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0006915 [apoptotic process]
GO:0007016 [cytoskeletal anchoring at plasma membrane]
GO:0008092 [cytoskeletal protein binding]
GO:0008150 [biological_process]
GO:0008360 [regulation of cell shape]
GO:0019898 [extrinsic component of membrane]
GO:0030673 [axolemma]
GO:0030865 [cortical cytoskeleton organization]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0030913 [paranodal junction assembly]
GO:0033270 [paranode region of axon]
GO:0043217 [myelin maintenance]
GO:0044224 [juxtaparanode region of axon]
GO:0048812 [neuron projection morphogenesis]
GO:0071205 [protein localization to juxtaparanode region of axon]
GO:0072659 [protein localization to plasma membrane]
Show all
 883 aa
98.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.