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EPYC

GENERAL INFORMATION

Gene name

 EPYC

Gene description

 Epiphycan

Protein class

 Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (placenta)
GTEx:Not detected
FANTOM5:Tissue enriched (placenta)

Protein evidence

 Evidence at protein level

Protein expression

 High expression in extracellular matrix.

DATA RELIABILITY

Data reliability
description

 Antibody staining in cells/structures not annotated, view images. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA038212 , HPA045455
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)

GENE INFORMATION

Gene name

 EPYC (HGNC Symbol)

Synonyms

 DSPG3, Pg-Lb, SLRR3B

Description

 Epiphycan (HGNC Symbol)

Entrez gene summary

 Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. [provided by RefSeq, Jul 2008]

Chromosome

 12

Cytoband

 q21.33

Chromosome location (bp)

 90963679 - 91005026

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000083782 (version 83.38)

Entrez gene

 1833

UniProt

 Q99645 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q99645

Antibodypedia

 EPYC antibodies

PROTEIN BROWSER
EPYC-001
EPYC-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EPYC-001
ENSP00000261172
ENST00000261172
Q99645 [Direct mapping]
Epiphycan
A0A024RBC3 [Target identity:100%; Query identity:100%]
Dermatan sulfate proteoglycan 3, isoform CRA_a
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   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
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GO:0005515 [protein binding]
GO:0005539 [glycosaminoglycan binding]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005615 [extracellular space]
GO:0007565 [female pregnancy]
GO:0008201 [heparin binding]
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 322 aa
36.6 kDa 		Yes 0
EPYC-002
ENSP00000448272
ENST00000551767
F8VSI4 [Direct mapping]
Epiphycan
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
Show all
 234 aa
26.4 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.