Expression of STARD7 in cancer - Summary - The Human Protein Atlas

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STARD7

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	STARD7
Gene description	StAR-related lipid transfer (START) domain containing 7
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression with a granular pattern in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA064978 , CAB033965
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), glioma (favourable), endometrial cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Glioma p<0.001 Endometrial cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA064978	CAB033965

GENE INFORMATION
Gene name	STARD7 (HGNC Symbol)
Synonyms	GTT1
Description	StAR-related lipid transfer (START) domain containing 7 (HGNC Symbol)
Entrez gene summary	Although the function of this gene is not known, its existence is supported by mRNA and EST data. The predicted gene product contains a region similar to the STAR-related lipid transfer (START) domain, which is often present in proteins involved in the cell signaling mediated by lipid binding. Alternatively spliced transcript variants have been described, although some transcripts occur only in cancer cell lines. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q11.2
Chromosome location (bp)	96184859 - 96208825
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000084090 (version 83.38)
Entrez gene	56910
UniProt	Q9NQZ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQZ5
Antibodypedia	STARD7 antibodies

PROTEIN BROWSER

STARD7-001	STARD7-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STARD7-001 ENSP00000338030 ENST00000337288	Q9NQZ5 [Direct mapping] StAR-related lipid transfer protein 7, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0008289 [lipid binding] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	370 aa 43.1 kDa	Yes	0
STARD7-006 ENSP00000409410 ENST00000443962	C9JTD3 [Direct mapping] StAR-related lipid transfer protein 7, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008289 [lipid binding] Show all	147 aa 17.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.