Cell atlas - BCORL1 - The Human Protein Atlas

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BCORL1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm
	Plasma membrane

Human cell
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	BCORL1
Gene description	BCL6 corepressor-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the plasma membrane.
RNA cell category	Cell line enhanced (AN3-CA)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Plasma membrane (uncertain)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA068568
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (AN3-CA) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the plasma membrane.

Main location

Nucleoplasm (supported)

Additional location

Plasma membrane (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA068568	CACO-2	Nucleoplasm
	HPA068568	CACO-2	Plasma membrane
	HPA068568	HEK 293	Nucleoplasm
	HPA068568	HEK 293	Plasma membrane
	HPA068568	U-2 OS	Nucleoplasm
	HPA068568	U-2 OS	Plasma membrane

GENE INFORMATION
Gene name	BCORL1 (HGNC Symbol)
Synonyms	CXorf10, FLJ11362
Description	BCL6 corepressor-like 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a transcriptional corepressor that is found tethered to promoter regions by DNA-binding proteins. The encoded protein can interact with several different class II histone deacetylases to repress transcription. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Chromosome	X
Cytoband	q26.1
Chromosome location (bp)	129981107 - 130058083
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000085185 (version 83.38)
Entrez gene	63035
UniProt	Q5H9F3 (UniProt - Evidence at protein level)
neXtProt	NX_Q5H9F3
Antibodypedia	BCORL1 antibodies

PROTEIN BROWSER

BCORL1-001	BCORL1-002	BCORL1-003	BCORL1-004	BCORL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BCORL1-001 ENSP00000218147 ENST00000218147	Q5H9F3 [Direct mapping] BCL-6 corepressor-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	1711 aa 182.5 kDa	No	0
BCORL1-002 ENSP00000484149 ENST00000607874	A0A087X1F0 [Direct mapping] BCL-6 corepressor-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		28 aa 3.2 kDa	No	0
BCORL1-003 ENSP00000399483 ENST00000456822	A0A075B6Q3 [Direct mapping] BCL-6 corepressor-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	1385 aa 150.6 kDa	No	0
BCORL1-004 ENSP00000416520 ENST00000441294	H7C4B2 [Direct mapping] BCL-6 corepressor-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		741 aa 79.3 kDa	No	0
BCORL1-201 ENSP00000437775 ENST00000540052	Q5H9F3 [Direct mapping] BCL-6 corepressor-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	1711 aa 182.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.