Cell atlas - AAMDC - The Human Protein Atlas

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AAMDC

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	AAMDC
Gene description	Adipogenesis associated, Mth938 domain containing
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA037918 , HPA037919
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (approved)

Additional location

Cytosol (approved)


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Antibody	Cell line	Location
HPA037918	A-431	Nucleoplasm
HPA037918	A-431	Cytosol
HPA037918	U-2 OS	Nucleoplasm
HPA037918	U-2 OS	Cytosol
HPA037918	U-251 MG	Nucleoplasm
HPA037919	A-431	Nucleoplasm
HPA037919	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	AAMDC (HGNC Symbol)
Synonyms	C11orf67, CK067, FLJ21035, PTD015
Description	Adipogenesis associated, Mth938 domain containing (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q14.1
Chromosome location (bp)	77821109 - 77918432
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000087884 (version 83.38)
Entrez gene	28971
UniProt	Q9H7C9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H7C9
Antibodypedia	AAMDC antibodies

PROTEIN BROWSER

AAMDC-001	AAMDC-002	AAMDC-003	AAMDC-005	AAMDC-007	AAMDC-008	AAMDC-009	AAMDC-010	AAMDC-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AAMDC-001 ENSP00000377078 ENST00000393427	Q9H7C9 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	122 aa 13.3 kDa	No	0
AAMDC-002 ENSP00000307254 ENST00000304716	K4DI89 [Direct mapping] Mth938 domain-containing protein; PTD015 protein, isoform CRA_c Show all	MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	147 aa 16.4 kDa	No	0
AAMDC-003 ENSP00000433293 ENST00000532481	Q9H7C9 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	88 aa 9.6 kDa	No	0
AAMDC-005 ENSP00000431808 ENST00000526415	Q9H7C9 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	122 aa 13.3 kDa	No	0
AAMDC-007 ENSP00000436086 ENST00000533193	E9PR47 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	168 aa 17.9 kDa	No	0
AAMDC-008 ENSP00000433956 ENST00000525409	E9PIQ4 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	90 aa 10 kDa	No	0
AAMDC-009 ENSP00000433281 ENST00000527134	E9PLK9 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	137 aa 15.2 kDa	No	0
AAMDC-010 ENSP00000432830 ENST00000525034	E9PNP3 [Direct mapping] Mth938 domain-containing protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	141 aa 15.6 kDa	No	0
AAMDC-201 ENSP00000486080 ENST00000630098	K4DI89 [Direct mapping] Mth938 domain-containing protein; PTD015 protein, isoform CRA_c Show all	MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	147 aa 16.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.