Cell atlas - EBF4 - The Human Protein Atlas

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EBF4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	EBF4
Gene description	Early B-cell factor 4
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SH-SY5Y)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	EBF4 (HGNC Symbol)
Synonyms	COE4, KIAA1442, O/E-4, RP5-860F19.3
Description	Early B-cell factor 4 (HGNC Symbol)
Entrez gene summary	EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation (Wang et al., 2002 [PubMed 12139918]).[supplied by OMIM, Mar 2008]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	2692878 - 2760108
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000088881 (version 83.38)
Entrez gene	57593
UniProt	Q9BQW3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BQW3
Antibodypedia	EBF4 antibodies

PROTEIN BROWSER

EBF4-006	EBF4-009	EBF4-011	EBF4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EBF4-006 ENSP00000477107 ENST00000463145	V9GYU8 [Direct mapping] Transcription factor COE4 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	177 aa 19.5 kDa	No	0
EBF4-009 ENSP00000345030 ENST00000342725	X6R549 [Direct mapping] Transcription factor COE4 Show all	SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	621 aa 66.3 kDa	No	0
EBF4-011 ENSP00000477023 ENST00000609451	Q9BQW3 [Direct mapping] Transcription factor COE4 Show all	Predicted intracellular proteins Transcription factors Immunoglobulin fold Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	602 aa 64.5 kDa	No	0
EBF4-201 ENSP00000370022 ENST00000380648	E9PEI2 [Direct mapping] Transcription factor COE4 Show all	Predicted intracellular proteins Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0008134 [transcription factor binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	598 aa 64 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.