Tissue expression of EBF4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	EBF4
Gene description	Early B-cell factor 4
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Mixed

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	EBF4 (HGNC Symbol)
Synonyms	COE4, KIAA1442, O/E-4, RP5-860F19.3
Description	Early B-cell factor 4 (HGNC Symbol)
Entrez gene summary	EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation (Wang et al., 2002 [PubMed 12139918]).[supplied by OMIM, Mar 2008]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	2692878 - 2760108
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000088881 (version 83.38)
Entrez gene	57593
UniProt	Q9BQW3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BQW3
Antibodypedia	EBF4 antibodies

PROTEIN BROWSER

EBF4-006	EBF4-009	EBF4-011	EBF4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EBF4-006 ENSP00000477107 ENST00000463145	V9GYU8 [Direct mapping] Transcription factor COE4 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	177 aa 19.5 kDa	No	0
EBF4-009 ENSP00000345030 ENST00000342725	X6R549 [Direct mapping] Transcription factor COE4 Show all	SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	621 aa 66.3 kDa	No	0
EBF4-011 ENSP00000477023 ENST00000609451	Q9BQW3 [Direct mapping] Transcription factor COE4 Show all	Predicted intracellular proteins Transcription factors Immunoglobulin fold Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	602 aa 64.5 kDa	No	0
EBF4-201 ENSP00000370022 ENST00000380648	E9PEI2 [Direct mapping] Transcription factor COE4 Show all	Predicted intracellular proteins Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0008134 [transcription factor binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0046983 [protein dimerization activity] Show all	598 aa 64 kDa	No	0