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RNA tissue category: Group enriched (liver, tonsil)
GENE INFORMATION
Gene name
FETUB
Synonyms
Description
Fetuin B (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008]
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003674 [molecular_function] GO:0004869 [cysteine-type endopeptidase inhibitor activity] GO:0005615 [extracellular space] GO:0007338 [single fertilization] GO:0007339 [binding of sperm to zona pellucida] GO:0008150 [biological_process] GO:0008191 [metalloendopeptidase inhibitor activity] GO:0010951 [negative regulation of endopeptidase activity] GO:0070062 [extracellular exosome]