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CAPN3

GENERAL INFORMATION

Gene name

 CAPN3

Gene description

 Calpain 3

Protein class

 Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 14
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (melanoma)
HPA (cell line):Cell line enriched (SK-MEL-30)
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in several tissues, most abundant in skeletal muscle.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA040052
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (melanoma)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA040052

GENE INFORMATION

Gene name

 CAPN3 (HGNC Symbol)

Synonyms

 CANP3, LGMD2, LGMD2A, nCL-1, p94

Description

 Calpain 3 (HGNC Symbol)

Entrez gene summary

 Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]

Chromosome

 15

Cytoband

 q15.1

Chromosome location (bp)

 42359500 - 42412318

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000092529 (version 83.38)

Entrez gene

 825

UniProt

 P20807 (UniProt - Evidence at protein level)

neXtProt

 NX_P20807

Antibodypedia

 CAPN3 antibodies

PROTEIN BROWSER
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CAPN3-005
CAPN3-006
CAPN3-007
CAPN3-008
CAPN3-009
CAPN3-010
CAPN3-011
CAPN3-012
CAPN3-013
CAPN3-015
CAPN3-017
CAPN3-019
CAPN3-201
CAPN3-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CAPN3-005
ENSP00000183936
ENST00000349748
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 729 aa
84.1 kDa 		No 0
CAPN3-006
ENSP00000336840
ENST00000337571
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 156 aa
18.2 kDa 		No 0
CAPN3-007
ENSP00000380384
ENST00000397200
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 309 aa
35.9 kDa 		No 0
CAPN3-008
ENSP00000350181
ENST00000357568
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 815 aa
93.5 kDa 		No 0
CAPN3-009
ENSP00000380349
ENST00000397163
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001896 [autolysis]
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045661 [regulation of myoblast differentiation]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0070315 [G1 to G0 transition involved in cell differentiation]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 821 aa
94.3 kDa 		No 0
CAPN3-010
ENSP00000454379
ENST00000569827
H3BMH1 [Direct mapping]
Calpain-3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 256 aa
29.9 kDa 		No 0
CAPN3-011
ENSP00000456607
ENST00000567071
H3BSA2 [Direct mapping]
Calpain-3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 188 aa
21.5 kDa 		No 0
CAPN3-012
ENSP00000380387
ENST00000397204
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 156 aa
18.2 kDa 		No 0
CAPN3-013
ENSP00000456575
ENST00000561817
H3BS77 [Direct mapping]
Calpain-3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 191 aa
22 kDa 		No 0
CAPN3-015
ENSP00000455254
ENST00000569136
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 156 aa
18.2 kDa 		No 0
CAPN3-017
ENSP00000457878
ENST00000565559
H3BUZ3 [Direct mapping]
Calpain-3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 157 aa
17.6 kDa 		No 0
CAPN3-019
ENSP00000457898
ENST00000564503
H3BV08 [Direct mapping]
Calpain-3
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 169 aa
19.5 kDa 		No 0
CAPN3-201
ENSP00000326281
ENST00000318023
F8W8F5 [Direct mapping]
Calpain-3
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0005509 [calcium ion binding]
GO:0005622 [intracellular]
GO:0006508 [proteolysis]
Show all
 773 aa
89 kDa 		No 0
CAPN3-202
ENSP00000348667
ENST00000356316
P20807 [Direct mapping]
Calpain-3
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003824 [catalytic activity]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0004871 [signal transducer activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006461 [protein complex assembly]
GO:0006508 [proteolysis]
GO:0006915 [apoptotic process]
GO:0007165 [signal transduction]
GO:0007517 [muscle organ development]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008307 [structural constituent of muscle]
GO:0014718 [positive regulation of satellite cell activation involved in skeletal muscle regeneration]
GO:0014850 [response to muscle activity]
GO:0030016 [myofibril]
GO:0030018 [Z disc]
GO:0030239 [myofibril assembly]
GO:0030315 [T-tubule]
GO:0031402 [sodium ion binding]
GO:0031432 [titin binding]
GO:0032947 [protein complex scaffold]
GO:0033234 [negative regulation of protein sumoylation]
GO:0043066 [negative regulation of apoptotic process]
GO:0043122 [regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043234 [protein complex]
GO:0045214 [sarcomere organization]
GO:0045862 [positive regulation of proteolysis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046716 [muscle cell cellular homeostasis]
GO:0050790 [regulation of catalytic activity]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051592 [response to calcium ion]
GO:0055103 [ligase regulator activity]
GO:0061061 [muscle structure development]
GO:0071277 [cellular response to calcium ion]
GO:0071472 [cellular response to salt stress]
GO:0072657 [protein localization to membrane]
GO:0097264 [self proteolysis]
Show all
 156 aa
18.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.