Cell atlas - TLL2 - The Human Protein Atlas

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TLL2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	TLL2
Gene description	Tolloid-like 2
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (RPTEC TERT1)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (RPTEC TERT1) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TLL2
Synonyms
Description	Tolloid-like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q24.1
Chromosome location (bp)	96364606 - 96513918
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000095587 (version 83.38)
Entrez gene	7093
UniProt	Q9Y6L7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y6L7
Antibodypedia	TLL2 antibodies

PROTEIN BROWSER

TLL2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TLL2-001 ENSP00000350630 ENST00000357947	Q9Y6L7 [Direct mapping] Tolloid-like protein 2 Show all	Enzymes Peptidases Metallopeptidases Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0004222 [metalloendopeptidase activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0006508 [proteolysis] GO:0007275 [multicellular organismal development] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] GO:0022617 [extracellular matrix disassembly] GO:0030154 [cell differentiation] GO:0030198 [extracellular matrix organization] Show all	1015 aa 113.6 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.