Cell atlas - HIVEP1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

HIVEP1

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria
	Nuclear bodies
	Nucleoplasm

Human cell
	Mitochondria
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	HIVEP1
Gene description	Human immunodeficiency virus type I enhancer binding protein 1
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the mitochondria & nuclear bodies.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Nuclear bodies (supported), Mitochondria (approved)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA050724
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the mitochondria & nuclear bodies.

Main location

Nucleoplasm (supported)

Additional location

Nuclear bodies (supported), Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA050724	HEK 293	Nucleoplasm
	HPA050724	HEK 293	Nuclear bodies
	HPA050724	MCF7	Nucleoplasm
	HPA050724	MCF7	Mitochondria
	HPA050724	U-2 OS	Nucleoplasm
	HPA050724	U-2 OS	Mitochondria

GENE INFORMATION
Gene name	HIVEP1 (HGNC Symbol)
Synonyms	CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A
Description	Human immunodeficiency virus type I enhancer binding protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a transcription factor belonging to the ZAS family, members of which are large proteins that contain a ZAS domain - a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specifically to the DNA sequence motif, GGGACTTTCC, found in the enhancer elements of several viral promoters, including human immunodeficiency virus (HIV), and to related sequences found in the enhancer elements of a number of cellular promoters. This protein binds to this sequence motif, suggesting a role in the transcriptional regulation of both viral and cellular genes. [provided by RefSeq, Oct 2011]
Chromosome	6
Cytoband	p24.1
Chromosome location (bp)	12008762 - 12164999
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000095951 (version 83.38)
Entrez gene	3096
UniProt	P15822 (UniProt - Evidence at protein level)
neXtProt	NX_P15822
Antibodypedia	HIVEP1 antibodies

PROTEIN BROWSER

HIVEP1-001	HIVEP1-002	HIVEP1-004	HIVEP1-005	HIVEP1-006	HIVEP1-007	HIVEP1-201	HIVEP1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HIVEP1-001 ENSP00000368698 ENST00000379388	P15822 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0001206 [transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006351 [transcription, DNA-templated] GO:0007165 [signal transduction] GO:0007275 [multicellular organismal development] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	2718 aa 296.8 kDa	No	0
HIVEP1-002 ENSP00000409078 ENST00000442081	C9JLG1 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	240 aa 26.5 kDa	No	0
HIVEP1-004 ENSP00000419762 ENST00000491710	C9JZF8 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		120 aa 13.5 kDa	No	0
HIVEP1-005 ENSP00000417348 ENST00000487103	C9J2N3 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		142 aa 15.9 kDa	No	0
HIVEP1-006 ENSP00000418021 ENST00000478545	C9JAW2 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		128 aa 14.3 kDa	No	0
HIVEP1-007 ENSP00000419721 ENST00000484210	C9JZV1 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		47 aa 5.2 kDa	No	0
HIVEP1-201 ENSP00000445617 ENST00000541134	F5H212 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	2717 aa 296.7 kDa	No	0
HIVEP1-202 ENSP00000486543 ENST00000627968	A0A0D9SFF3 [Direct mapping] Zinc finger protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	583 aa 62.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.