Tissue expression of HNRNPH3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	HNRNPH3
Gene description	Heterogeneous nuclear ribonucleoprotein H3 (2H9)
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	HNRNPH3 (HGNC Symbol)
Synonyms	2H9, HNRPH3
Description	Heterogeneous nuclear ribonucleoprotein H3 (2H9) (HGNC Symbol)
Entrez gene summary	This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q21.3
Chromosome location (bp)	68331174 - 68343191
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000096746 (version 83.38)
Entrez gene	3189
UniProt	P31942 (UniProt - Evidence at protein level)
neXtProt	NX_P31942
Antibodypedia	HNRNPH3 antibodies

PROTEIN BROWSER

HNRNPH3-003	HNRNPH3-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HNRNPH3-003 ENSP00000346726 ENST00000354695	P31942 [Direct mapping] Heterogeneous nuclear ribonucleoprotein H3 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000398 [mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] GO:0006396 [RNA processing] GO:0008380 [RNA splicing] GO:0030855 [epithelial cell differentiation] GO:0044822 [poly(A) RNA binding] Show all	331 aa 35.2 kDa	No	0
HNRNPH3-012 ENSP00000265866 ENST00000265866	P31942 [Direct mapping] Heterogeneous nuclear ribonucleoprotein H3 A0A024QZK8 [Target identity:100%; Query identity:100%] Heterogeneous nuclear ribonucleoprotein H3 (2H9), isoform CRA_a Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000398 [mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] GO:0006396 [RNA processing] GO:0008380 [RNA splicing] GO:0030855 [epithelial cell differentiation] GO:0044822 [poly(A) RNA binding] Show all	346 aa 36.9 kDa	No	0