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YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]
P25490 [Direct mapping] Transcriptional repressor protein YY1
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Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000400 [four-way junction DNA binding] GO:0000724 [double-strand break repair via homologous recombination] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0001158 [enhancer sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0003713 [transcription coactivator activity] GO:0003714 [transcription corepressor activity] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006403 [RNA localization] GO:0006974 [cellular response to DNA damage stimulus] GO:0007283 [spermatogenesis] GO:0008270 [zinc ion binding] GO:0009952 [anterior/posterior pattern specification] GO:0010225 [response to UV-C] GO:0010628 [positive regulation of gene expression] GO:0010629 [negative regulation of gene expression] GO:0016363 [nuclear matrix] GO:0030154 [cell differentiation] GO:0031011 [Ino80 complex] GO:0031519 [PcG protein complex] GO:0034644 [cellular response to UV] GO:0034696 [response to prostaglandin F] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0044212 [transcription regulatory region DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046332 [SMAD binding] GO:0046872 [metal ion binding] GO:0048593 [camera-type eye morphogenesis] GO:0051276 [chromosome organization] GO:0071347 [cellular response to interleukin-1]