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BRMS1L

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GENERAL INFORMATION

Gene name

 BRMS1L

Gene description

 Breast cancer metastasis-suppressor 1-like

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleoplasm.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (supported)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA046623
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ASSAYS
RNA expression
Human cells
Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleoplasm.

Main location

 Nucleoplasm (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA046623 A-431 Nucleoplasm
Cytosol
HPA046623 MCF7 Nucleoplasm
HPA046623 U-2 OS Nucleoplasm

MOUSE CELLS

Main location

 Not available

Mouse gene

 ENSMUSG00000012076 (version 83)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location
HPA046623 NIH 3T3 Nucleus
Cytosol

GENE INFORMATION

Gene name

 BRMS1L (HGNC Symbol)

Synonyms

 BRMS1, FLJ39177, MGC11296

Description

 Breast cancer metastasis-suppressor 1-like (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC). [provided by RefSeq, Jul 2008]

Chromosome

 14

Cytoband

 q13.2

Chromosome location (bp)

 35826318 - 35932325

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000100916 (version 83.38)

Entrez gene

 84312

UniProt

 Q5PSV4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5PSV4

Antibodypedia

 BRMS1L antibodies

PROTEIN BROWSER
BRMS1L-001
BRMS1L-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BRMS1L-001
ENSP00000216807
ENST00000216807
Q5PSV4 [Direct mapping]
Breast cancer metastasis-suppressor 1-like protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0004407 [histone deacetylase activity]
GO:0005515 [protein binding]
GO:0006351 [transcription, DNA-templated]
GO:0016575 [histone deacetylation]
GO:0040008 [regulation of growth]
GO:0042826 [histone deacetylase binding]
GO:0070822 [Sin3-type complex]
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 323 aa
37.6 kDa 		No 0
BRMS1L-006
ENSP00000446826
ENST00000551774
H0YHD0 [Direct mapping]
Breast cancer metastasis-suppressor 1-like protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0004407 [histone deacetylase activity]
GO:0016575 [histone deacetylation]
GO:0042826 [histone deacetylase binding]
GO:0070822 [Sin3-type complex]
Show all
 215 aa
25 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.