Expression of PRELID3B in cancer - Summary - The Human Protein Atlas

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PRELID3B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRELID3B
Gene description	PRELI domain containing 3B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA047721
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and endometrial cancer (unfavourable).
Liver cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047721

GENE INFORMATION
Gene name	PRELID3B (HGNC Symbol)
Synonyms	C20orf45, dJ543J19.5, SLMO2
Description	PRELI domain containing 3B (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	q13.32
Chromosome location (bp)	59033145 - 59042909
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101166 (version 83.38)
Entrez gene	51012
UniProt	Q9Y3B1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y3B1
Antibodypedia	PRELID3B antibodies

PROTEIN BROWSER

PRELID3B-001	PRELID3B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRELID3B-001 ENSP00000360072 ENST00000371033	Q9Y3B1 [Direct mapping] Protein slowmo homolog 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005758 [mitochondrial intermembrane space] GO:0015914 [phospholipid transport] GO:1990050 [phosphatidic acid transporter activity] Show all	164 aa 18.2 kDa	No	0
PRELID3B-002 ENSP00000348206 ENST00000355937	Q9Y3B1 [Direct mapping] Protein slowmo homolog 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005758 [mitochondrial intermembrane space] GO:0015914 [phospholipid transport] GO:1990050 [phosphatidic acid transporter activity] Show all	194 aa 21.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.