Cell atlas - SLC52A3 - The Human Protein Atlas

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SLC52A3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SLC52A3
Gene description	Solute carrier family 52 (riboflavin transporter), member 3
Protein class	Disease related genes Plasma proteins Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (CAPAN-2, T-47d, SK-BR-3)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (CAPAN-2, T-47d, SK-BR-3) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SLC52A3 (HGNC Symbol)
Synonyms	bA371L19.1, C20orf54, hRFT2, RFVT3
Description	Solute carrier family 52 (riboflavin transporter), member 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease. [provided by RefSeq, Mar 2012]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	760080 - 776015
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101276 (version 83.38)
Entrez gene	113278
UniProt	Q9NQ40 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NQ40
Antibodypedia	SLC52A3 antibodies

PROTEIN BROWSER

SLC52A3-001	SLC52A3-004	SLC52A3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC52A3-001 ENSP00000217254 ENST00000217254	Q9NQ40 [Direct mapping] Solute carrier family 52, riboflavin transporter, member 3 K0A6P4 [Target identity:100%; Query identity:100%] Chromosome 20 open reading frame 54, isoform CRA_c; Solute carrier family 52 member 3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Disease related genes Potential drug targets Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0006771 [riboflavin metabolic process] GO:0007605 [sensory perception of sound] GO:0016324 [apical plasma membrane] GO:0032217 [riboflavin transporter activity] GO:0032218 [riboflavin transport] GO:0044281 [small molecule metabolic process] Show all	469 aa 50.8 kDa	Yes	>9
SLC52A3-004 ENSP00000371370 ENST00000381944	Q9NQ40 [Direct mapping] Solute carrier family 52, riboflavin transporter, member 3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Plasma proteins Disease related genes Potential drug targets Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0006771 [riboflavin metabolic process] GO:0007605 [sensory perception of sound] GO:0016324 [apical plasma membrane] GO:0032217 [riboflavin transporter activity] GO:0032218 [riboflavin transport] GO:0044281 [small molecule metabolic process] Show all	415 aa 45 kDa	Yes	8
SLC52A3-201 ENSP00000488723 ENST00000632431	Q9NQ40 [Direct mapping] Solute carrier family 52, riboflavin transporter, member 3 K0A6P4 [Target identity:100%; Query identity:100%] Chromosome 20 open reading frame 54, isoform CRA_c; Solute carrier family 52 member 3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0006771 [riboflavin metabolic process] GO:0007605 [sensory perception of sound] GO:0016324 [apical plasma membrane] GO:0032217 [riboflavin transporter activity] GO:0032218 [riboflavin transport] GO:0034605 [cellular response to heat] GO:0044281 [small molecule metabolic process] Show all	469 aa 50.8 kDa	No	>9

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.