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Cancer tissues showed moderate to strong cytoplasmic staining with additional nuclear staining in many cases. Several cases of gliomas and lymphomas were weakly stained or negative.
GENE INFORMATION
Gene name
ANKRD12 (HGNC Symbol)
Synonyms
FLJ20053, GAC-1, KIAA0874
Description
Ankyrin repeat domain 12 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Q6UB98 [Direct mapping] Ankyrin repeat domain-containing protein 12
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Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q6UB98 [Direct mapping] Ankyrin repeat domain-containing protein 12
Show all
Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)