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CAPN15

GENERAL INFORMATION

Gene name

 CAPN15

Gene description

 Calpain 15

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 High cytoplasmic expression in a few tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA011960
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CAPN15 (HGNC Symbol)

Synonyms

 SOLH

Description

 Calpain 15 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p13.3

Chromosome location (bp)

 527717 - 554636

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000103326 (version 83.38)

Entrez gene

 6650

UniProt

 O75808 (UniProt - Evidence at protein level)

neXtProt

 NX_O75808

Antibodypedia

 CAPN15 antibodies

PROTEIN BROWSER
CAPN15-001
CAPN15-005
CAPN15-006
CAPN15-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CAPN15-001
ENSP00000219611
ENST00000219611
O75808 [Direct mapping]
Calpain-15
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Enzymes
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004198 [calcium-dependent cysteine-type endopeptidase activity]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006508 [proteolysis]
GO:0008233 [peptidase activity]
GO:0008234 [cysteine-type peptidase activity]
GO:0008270 [zinc ion binding]
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 1086 aa
117.3 kDa 		No 0
CAPN15-005
ENSP00000456017
ENST00000562370
H3BR03 [Direct mapping]
Calpain-15
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
GO:0008270 [zinc ion binding]
Show all
 185 aa
19.9 kDa 		No 0
CAPN15-006
ENSP00000457030
ENST00000568988
H3BT55 [Direct mapping]
Calpain-15
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
Show all
 112 aa
11.9 kDa 		No 0
CAPN15-008
ENSP00000457306
ENST00000566977
H3BTS4 [Direct mapping]
Calpain-15
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006508 [proteolysis]
Show all
 71 aa
7.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.