Tissue expression of EIF3E - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

EIF3E

TISSUE

premium

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	EIF3E
Gene description	Eukaryotic translation initiation factor 3, subunit E
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic and nuclear expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA023973
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	EIF3E (HGNC Symbol)
Synonyms	eIF3-p48, eIF3e, EIF3S6, INT6
Description	Eukaryotic translation initiation factor 3, subunit E (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q23.1
Chromosome location (bp)	108201216 - 108435333
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104408 (version 83.38)
Entrez gene	3646
UniProt	P60228 (UniProt - Evidence at protein level)
neXtProt	NX_P60228
Antibodypedia	EIF3E antibodies

PROTEIN BROWSER

EIF3E-001	EIF3E-002	EIF3E-007	EIF3E-008	EIF3E-010	EIF3E-011	EIF3E-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EIF3E-001 ENSP00000220849 ENST00000220849	P60228 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000785 [chromatin] GO:0001731 [formation of translation preinitiation complex] GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016282 [eukaryotic 43S preinitiation complex] GO:0016605 [PML body] GO:0033290 [eukaryotic 48S preinitiation complex] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding] GO:0045947 [negative regulation of translational initiation] GO:0047485 [protein N-terminus binding] GO:0070062 [extracellular exosome] Show all	445 aa 52.2 kDa	No	0
EIF3E-002 ENSP00000428796 ENST00000519030	E5RGA2 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0001731 [formation of translation preinitiation complex] GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006446 [regulation of translational initiation] GO:0016282 [eukaryotic 43S preinitiation complex] GO:0016605 [PML body] GO:0033290 [eukaryotic 48S preinitiation complex] Show all	352 aa 41.4 kDa	No	0
EIF3E-007 ENSP00000430678 ENST00000518345	E5RIT4 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	75 aa 8.9 kDa	No	0
EIF3E-008 ENSP00000430839 ENST00000519627	E5RHS5 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	226 aa 26.6 kDa	No	0
EIF3E-010 ENSP00000429968 ENST00000521297	H0YBP5 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	74 aa 8.4 kDa	No	0
EIF3E-011 ENSP00000430152 ENST00000521440	H0YBR5 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	171 aa 20.1 kDa	No	0
EIF3E-015 ENSP00000428170 ENST00000522352	H0YAW4 [Direct mapping] Eukaryotic translation initiation factor 3 subunit E Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	156 aa 18 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.