Tissue expression of CD79A - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CD79A

premium

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CD79A
Gene description	CD79a molecule, immunoglobulin-associated alpha
Protein class	Cancer-related genes CD markers Disease related genes Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (appendix, lymph node, spleen, tonsil)
GTEx:	Group enriched (small intestine, spleen)
FANTOM5:	Group enriched (appendix, lymph node, spleen, tonsil)

Protein evidence

Evidence at protein level

Protein expression

Distinct cytoplasmic expression in a subset of immune cells, mainly in lymphoid tissue.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. CAB000019
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (appendix, lymph node, spleen, tonsil)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (small intestine, spleen)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (appendix, lymph node, spleen, tonsil)

GENE INFORMATION
Gene name	CD79A (HGNC Symbol)
Synonyms	IGA, MB-1
Description	CD79a molecule, immunoglobulin-associated alpha (HGNC Symbol)
Entrez gene summary	The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	q13.2
Chromosome location (bp)	41877120 - 41881372
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105369 (version 83.38)
Entrez gene	973
UniProt	P11912 (UniProt - Evidence at protein level)
neXtProt	NX_P11912
Antibodypedia	CD79A antibodies

PROTEIN BROWSER

CD79A-001	CD79A-002	CD79A-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD79A-001 ENSP00000221972 ENST00000221972	P11912 [Direct mapping] B-cell antigen receptor complex-associated protein alpha chain Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002250 [adaptive immune response] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005771 [multivesicular body] GO:0005886 [plasma membrane] GO:0007166 [cell surface receptor signaling pathway] GO:0009897 [external side of plasma membrane] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019815 [B cell receptor complex] GO:0030183 [B cell differentiation] GO:0042100 [B cell proliferation] GO:0042113 [B cell activation] GO:0045121 [membrane raft] GO:0050853 [B cell receptor signaling pathway] Show all	226 aa 25 kDa	Yes	1
CD79A-002 ENSP00000400605 ENST00000444740	P11912 [Direct mapping] B-cell antigen receptor complex-associated protein alpha chain Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002250 [adaptive immune response] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005771 [multivesicular body] GO:0005886 [plasma membrane] GO:0007166 [cell surface receptor signaling pathway] GO:0009897 [external side of plasma membrane] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019815 [B cell receptor complex] GO:0030183 [B cell differentiation] GO:0042100 [B cell proliferation] GO:0042113 [B cell activation] GO:0045121 [membrane raft] GO:0050853 [B cell receptor signaling pathway] Show all	188 aa 20.8 kDa	Yes	1
CD79A-003 ENSP00000468922 ENST00000597454	M0QX61 [Direct mapping] B-cell antigen receptor complex-associated protein alpha chain Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	258 aa 27.9 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.