Expression of GLTSCR2 in cancer - Summary - The Human Protein Atlas

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GLTSCR2

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GLTSCR2
Gene description	Glioma tumor suppressor candidate region gene 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nucleolar expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA018999
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA018999

GENE INFORMATION
Gene name	GLTSCR2 (HGNC Symbol)
Synonyms	PICT-1
Description	Glioma tumor suppressor candidate region gene 2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	47745522 - 47757058
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105373 (version 83.38)
Entrez gene	29997
UniProt	Q9NZM5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NZM5
Antibodypedia	GLTSCR2 antibodies

PROTEIN BROWSER

GLTSCR2-001	GLTSCR2-009	GLTSCR2-010	GLTSCR2-011	GLTSCR2-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLTSCR2-001 ENSP00000246802 ENST00000246802	Q9NZM5 [Direct mapping] Glioma tumor suppressor candidate region gene 2 protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005730 [nucleolus] GO:0008150 [biological_process] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	478 aa 54.4 kDa	No	0
GLTSCR2-009 ENSP00000470263 ENST00000597985	M0QZ34 [Direct mapping] Glioma tumor suppressor candidate region gene 2 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005730 [nucleolus] GO:0043231 [intracellular membrane-bounded organelle] Show all	200 aa 23.5 kDa	No	0
GLTSCR2-010 ENSP00000470190 ENST00000598959	M0QYZ9 [Direct mapping] Glioma tumor suppressor candidate region gene 2 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		149 aa 17.4 kDa	No	0
GLTSCR2-011 ENSP00000468948 ENST00000595143	M0QX73 [Direct mapping] Glioma tumor suppressor candidate region gene 2 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		265 aa 29.6 kDa	No	0
GLTSCR2-013 ENSP00000470773 ENST00000594182	M0QZU5 [Direct mapping] Glioma tumor suppressor candidate region gene 2 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005730 [nucleolus] GO:0043231 [intracellular membrane-bounded organelle] Show all	99 aa 12 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.