Cell atlas - MIER2 - The Human Protein Atlas

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MIER2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	MIER2
Gene description	Mesoderm induction early response 1, family member 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol & nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA041439
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol & nucleoplasm.

Main location

Nucleoplasm (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041439	A-431	Nucleoplasm
	HPA041439	A-431	Cytosol
	HPA041439	U-2 OS	Nucleoplasm
	HPA041439	U-2 OS	Cytosol
	HPA041439	U-251 MG	Nucleoplasm
	HPA041439	U-251 MG	Cytosol

GENE INFORMATION
Gene name	MIER2 (HGNC Symbol)
Synonyms	KIAA1193
Description	Mesoderm induction early response 1, family member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	301444 - 344807
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105556 (version 83.38)
Entrez gene	54531
UniProt	Q8N344 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N344
Antibodypedia	MIER2 antibodies

PROTEIN BROWSER

MIER2-001	MIER2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MIER2-001 ENSP00000264819 ENST00000264819	Q8N344 [Direct mapping] Mesoderm induction early response protein 2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	545 aa 59.9 kDa	No	0
MIER2-006 ENSP00000482489 ENST00000619835	A0A087WZA4 [Direct mapping] Mesoderm induction early response protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		210 aa 22.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.