Cell atlas - DDX49 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	DDX49
Gene description	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria. In addition localized to the nucleoli.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (approved)
Additional location	In addition localized to the Nucleoli (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA048093
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria. In addition localized to the nucleoli.

Main location

Mitochondria (approved)

Additional location

Nucleoli (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA048093	A-431	Mitochondria
HPA048093	PC-3	Mitochondria
HPA048093	U-2 OS	Nucleoli
HPA048093	U-2 OS	Mitochondria

MOUSE CELLS

Main location

Not available

Mouse gene

ENSMUSG00000057788 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA048093	NIH 3T3	No staining

GENE INFORMATION
Gene name	DDX49 (HGNC Symbol)
Synonyms	FLJ10432
Description	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	18919675 - 18928633
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105671 (version 83.38)
Entrez gene	54555
UniProt	Q9Y6V7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y6V7
Antibodypedia	DDX49 antibodies

PROTEIN BROWSER

DDX49-001	DDX49-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DDX49-001 ENSP00000247003 ENST00000247003	Q9Y6V7 [Direct mapping] Probable ATP-dependent RNA helicase DDX49 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005524 [ATP binding] GO:0010501 [RNA secondary structure unwinding] GO:0044822 [poly(A) RNA binding] Show all	483 aa 54.2 kDa	No	0
DDX49-201 ENSP00000487048 ENST00000629999	M0R0K1 [Direct mapping] DEAD (Asp-Glu-Ala-Asp) box polypeptide 49, isoform CRA_c; Probable ATP-dependent RNA helicase DDX49 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0005524 [ATP binding] GO:0010501 [RNA secondary structure unwinding] Show all	166 aa 17.7 kDa	No	0