Tissue expression of H2AFV - Summary - The Human Protein Atlas

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H2AFV

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	H2AFV
Gene description	H2A histone family, member V
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous nuclear expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA057236
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	H2AFV (HGNC Symbol)
Synonyms	H2AV, MGC10170, MGC10831, MGC1947
Description	H2A histone family, member V (HGNC Symbol)
Entrez gene summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]
Chromosome	7
Cytoband	p13
Chromosome location (bp)	44826791 - 44848083
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105968 (version 83.38)
Entrez gene	94239
UniProt	Q71UI9 (UniProt - Evidence at protein level)
neXtProt	NX_Q71UI9
Antibodypedia	H2AFV antibodies

PROTEIN BROWSER

H2AFV-001	H2AFV-002	H2AFV-003	H2AFV-004	H2AFV-005	H2AFV-006	H2AFV-007	H2AFV-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
H2AFV-001 ENSP00000222690 ENST00000222690	Q71UI9 [Direct mapping] Histone H2A.V Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0008150 [biological_process] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	114 aa 12.1 kDa	No	0
H2AFV-002 ENSP00000308405 ENST00000308153	Q71UI9 [Direct mapping] Histone H2A.V Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0008150 [biological_process] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	128 aa 13.5 kDa	No	0
H2AFV-003 ENSP00000340708 ENST00000350771	Q71UI9 [Direct mapping] Histone H2A.V Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0008150 [biological_process] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	102 aa 11 kDa	No	0
H2AFV-004 ENSP00000342714 ENST00000349299	Q71UI9 [Direct mapping] Histone H2A.V Show all	Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0008150 [biological_process] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	90 aa 9.4 kDa	No	0
H2AFV-005 ENSP00000397115 ENST00000437072	C9J386 [Direct mapping] Histone H2A Show all	Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0046982 [protein heterodimerization activity] Show all	76 aa 8 kDa	No	0
H2AFV-006 ENSP00000406901 ENST00000446531	C9J0D1 [Direct mapping] Histone H2A Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0046982 [protein heterodimerization activity] Show all	122 aa 13.2 kDa	No	0
H2AFV-007 ENSP00000370516 ENST00000381124	Q71UI9 [Direct mapping] Histone H2A.V Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0000790 [nuclear chromatin] GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0008150 [biological_process] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	66 aa 6.9 kDa	No	0
H2AFV-008 ENSP00000430492 ENST00000521529	E5RJU1 [Direct mapping] Histone H2A.V Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0046982 [protein heterodimerization activity] Show all	40 aa 4.4 kDa	No	0

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The Human Protein Atlas

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