Tissue expression of ABHD11 - Summary - The Human Protein Atlas

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ABHD11

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ABHD11
Gene description	Abhydrolase domain containing 11
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA024042 , HPA049641
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ABHD11 (HGNC Symbol)
Synonyms	PP1226, WBSCR21
Description	Abhydrolase domain containing 11 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q11.23
Chromosome location (bp)	73736094 - 73738867
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000106077 (version 83.38)
Entrez gene	83451
UniProt	Q8NFV4 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NFV4
Antibodypedia	ABHD11 antibodies

PROTEIN BROWSER

ABHD11-001	ABHD11-003	ABHD11-007	ABHD11-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD11-001 ENSP00000222800 ENST00000222800	Q8NFV4 [Direct mapping] Alpha/beta hydrolase domain-containing protein 11 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	315 aa 34.7 kDa	No	0
ABHD11-003 ENSP00000416970 ENST00000437775	Q8NFV4 [Direct mapping] Alpha/beta hydrolase domain-containing protein 11 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	308 aa 33.9 kDa	No	0
ABHD11-007 ENSP00000378579 ENST00000395147	Q8NFV4 [Direct mapping] Alpha/beta hydrolase domain-containing protein 11 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	258 aa 28.5 kDa	No	0
ABHD11-009 ENSP00000397666 ENST00000458339	C9J7Q4 [Direct mapping] Alpha/beta hydrolase domain-containing protein 11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		159 aa 17 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.