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BCL7B

GENERAL INFORMATION

Gene name

 BCL7B

Gene description

 B-cell CLL/lymphoma 7B

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA058069
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 BCL7B

Synonyms

Description

 B-cell CLL/lymphoma 7B (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]

Chromosome

 7

Cytoband

 q11.23

Chromosome location (bp)

 73536356 - 73558002

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000106635 (version 83.38)

Entrez gene

 9275

UniProt

 Q9BQE9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BQE9

Antibodypedia

 BCL7B antibodies

PROTEIN BROWSER
BCL7B-001
BCL7B-002
BCL7B-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BCL7B-001
ENSP00000223368
ENST00000223368
Q9BQE9 [Direct mapping]
B-cell CLL/lymphoma 7 protein family member B
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Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
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 202 aa
22.2 kDa 		No 0
BCL7B-002
ENSP00000393230
ENST00000411832
Q9BQE9 [Direct mapping]
B-cell CLL/lymphoma 7 protein family member B
Show all
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
Show all
 145 aa
16 kDa 		No 0
BCL7B-006
ENSP00000411073
ENST00000455335
F2Z3H6 [Direct mapping]
B-cell CLL/lymphoma 7 protein family member B; B-cell CLL/lymphoma 7B, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 213 aa
23.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.