Fields »
ABOUT
HELP
BLOG
GIT1

GENERAL INFORMATION

Gene name

 GIT1

Gene description

 G protein-coupled receptor kinase interacting ArfGAP 1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA004059 , HPA004186
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GIT1

Synonyms

Description

 G protein-coupled receptor kinase interacting ArfGAP 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q11.2

Chromosome location (bp)

 29573469 - 29594054

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000108262 (version 83.38)

Entrez gene

 28964

UniProt

 Q9Y2X7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2X7

Antibodypedia

 GIT1 antibodies

PROTEIN BROWSER
GIT1-001
GIT1-003
GIT1-006
GIT1-008
GIT1-011
GIT1-012
GIT1-015
GIT1-016
GIT1-017

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GIT1-001
ENSP00000225394
ENST00000225394
Q9Y2X7 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005925 [focal adhesion]
GO:0007411 [axon guidance]
GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway]
GO:0016020 [membrane]
GO:0016235 [aggresome]
GO:0032465 [regulation of cytokinesis]
GO:0043547 [positive regulation of GTPase activity]
GO:0046872 [metal ion binding]
GO:0048013 [ephrin receptor signaling pathway]
Show all
 761 aa
84.3 kDa 		No 0
GIT1-003
ENSP00000378338
ENST00000394869
Q9Y2X7 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005925 [focal adhesion]
GO:0007411 [axon guidance]
GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway]
GO:0016020 [membrane]
GO:0016235 [aggresome]
GO:0032403 [protein complex binding]
GO:0032465 [regulation of cytokinesis]
GO:0043547 [positive regulation of GTPase activity]
GO:0046872 [metal ion binding]
GO:0048013 [ephrin receptor signaling pathway]
Show all
 770 aa
85.4 kDa 		No 0
GIT1-006
ENSP00000464388
ENST00000579937
J3QRU8 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005925 [focal adhesion]
GO:0016235 [aggresome]
GO:0043547 [positive regulation of GTPase activity]
GO:0046872 [metal ion binding]
Show all
 694 aa
76.8 kDa 		No 0
GIT1-008
ENSP00000462775
ENST00000581348
A0A0C4DGN6 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0043547 [positive regulation of GTPase activity]
Show all
 747 aa
83.1 kDa 		No 0
GIT1-011
ENSP00000334125
ENST00000335356
E7EVC2 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 147 aa
15.4 kDa 		No 0
GIT1-012
ENSP00000464933
ENST00000577466
K7EIX6 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 52 aa
5.9 kDa 		No 0
GIT1-015
ENSP00000466824
ENST00000583413
K7EN79 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0043547 [positive regulation of GTPase activity]
Show all
 173 aa
19.2 kDa 		No 0
GIT1-016
ENSP00000463543
ENST00000585148
J3QLH1 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 229 aa
25.8 kDa 		No 0
GIT1-017
ENSP00000463435
ENST00000578266
J3QL89 [Direct mapping]
ARF GTPase-activating protein GIT1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005925 [focal adhesion]
Show all
 177 aa
19 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.