Cell atlas - CAMTA2 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CAMTA2
Gene description	Calmodulin binding transcription activator 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleus. In addition localized to the mitochondria & actin filaments.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved)
Additional location	In addition localized to the Actin filaments (approved), Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051147
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ASSAYS

RNA expression

Human cells

Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleus. In addition localized to the mitochondria & actin filaments.

Main location

Nucleus (approved)

Additional location

Actin filaments (approved), Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA051147	HEK 293	Nucleus
HPA051147	U-2 OS	Nucleus
		Actin filaments
		Mitochondria
HPA051147	U-251 MG	Nucleoplasm

MOUSE CELLS

Main location

Not available

Mouse gene

ENSMUSG00000040712 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA051147	NIH 3T3	No staining

GENE INFORMATION
Gene name	CAMTA2 (HGNC Symbol)
Synonyms	KIAA0909
Description	Calmodulin binding transcription activator 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
Chromosome	17
Cytoband	p13.2
Chromosome location (bp)	4967992 - 4987652
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108509 (version 83.38)
Entrez gene	23125
UniProt	O94983 (UniProt - Evidence at protein level)
neXtProt	NX_O94983
Antibodypedia	CAMTA2 antibodies

PROTEIN BROWSER

CAMTA2-001	CAMTA2-002	CAMTA2-003	CAMTA2-004	CAMTA2-007	CAMTA2-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CAMTA2-001 ENSP00000321813 ENST00000348066	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1202 aa 131.5 kDa	No	0
CAMTA2-002 ENSP00000354828 ENST00000361571	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1201 aa 130.9 kDa	No	0
CAMTA2-003 ENSP00000412886 ENST00000414043	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1241 aa 134.8 kDa	No	0
CAMTA2-004 ENSP00000370712 ENST00000381311	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1197 aa 130.7 kDa	No	0
CAMTA2-007 ENSP00000460779 ENST00000572543	I3L3W6 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	1207 aa 132.1 kDa	No	0
CAMTA2-010 ENSP00000459519 ENST00000574606	I3L2A1 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	178 aa 20.7 kDa	No	0