Expression of CAMTA2 in cancer - Summary - The Human Protein Atlas

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CAMTA2

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	CAMTA2
Gene description	Calmodulin binding transcription activator 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	CAMTA2 (HGNC Symbol)
Synonyms	KIAA0909
Description	Calmodulin binding transcription activator 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
Chromosome	17
Cytoband	p13.2
Chromosome location (bp)	4967992 - 4987652
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108509 (version 83.38)
Entrez gene	23125
UniProt	O94983 (UniProt - Evidence at protein level)
neXtProt	NX_O94983
Antibodypedia	CAMTA2 antibodies

PROTEIN BROWSER

CAMTA2-001	CAMTA2-002	CAMTA2-003	CAMTA2-004	CAMTA2-007	CAMTA2-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CAMTA2-001 ENSP00000321813 ENST00000348066	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1202 aa 131.5 kDa	No	0
CAMTA2-002 ENSP00000354828 ENST00000361571	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1201 aa 130.9 kDa	No	0
CAMTA2-003 ENSP00000412886 ENST00000414043	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1241 aa 134.8 kDa	No	0
CAMTA2-004 ENSP00000370712 ENST00000381311	O94983 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0008134 [transcription factor binding] GO:0014898 [cardiac muscle hypertrophy in response to stress] GO:0042826 [histone deacetylase binding] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	1197 aa 130.7 kDa	No	0
CAMTA2-007 ENSP00000460779 ENST00000572543	I3L3W6 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	1207 aa 132.1 kDa	No	0
CAMTA2-010 ENSP00000459519 ENST00000574606	I3L2A1 [Direct mapping] Calmodulin-binding transcription activator 2 Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	178 aa 20.7 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
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