Tissue expression of SMARCD2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SMARCD2
Gene description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SMARCD2 (HGNC Symbol)
Synonyms	BAF60B, CRACD2, PRO2451, Rsc6p
Description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q23.3
Chromosome location (bp)	63832081 - 63843065
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108604 (version 83.38)
Entrez gene	6603
UniProt	Q92925 (UniProt - Evidence at protein level)
neXtProt	NX_Q92925
Antibodypedia	SMARCD2 antibodies

PROTEIN BROWSER

SMARCD2-001	SMARCD2-002	SMARCD2-003	SMARCD2-005	SMARCD2-012	SMARCD2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SMARCD2-001 ENSP00000392617 ENST00000448276	Q92925 [Direct mapping] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000790 [nuclear chromatin] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006337 [nucleosome disassembly] GO:0006338 [chromatin remodeling] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016514 [SWI/SNF complex] GO:0031492 [nucleosomal DNA binding] GO:0043044 [ATP-dependent chromatin remodeling] GO:0043234 [protein complex] GO:0090544 [BAF-type complex] Show all	531 aa 58.9 kDa	No	0
SMARCD2-002 ENSP00000225742 ENST00000225742	J3KMX2 [Direct mapping] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0016514 [SWI/SNF complex] GO:0043044 [ATP-dependent chromatin remodeling] Show all	456 aa 52.2 kDa	No	0
SMARCD2-003 ENSP00000318451 ENST00000323347	Q92925 [Direct mapping] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000790 [nuclear chromatin] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006337 [nucleosome disassembly] GO:0006338 [chromatin remodeling] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016514 [SWI/SNF complex] GO:0031492 [nucleosomal DNA binding] GO:0043044 [ATP-dependent chromatin remodeling] GO:0043234 [protein complex] Show all	483 aa 55.2 kDa	No	0
SMARCD2-005 ENSP00000462761 ENST00000577990	J3KT18 [Direct mapping] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		69 aa 6 kDa	No	0
SMARCD2-012 ENSP00000398946 ENST00000450364	J3QWB6 [Direct mapping] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016514 [SWI/SNF complex] GO:0043044 [ATP-dependent chromatin remodeling] Show all	231 aa 26.7 kDa	No	0
SMARCD2-201 ENSP00000483605 ENST00000613943	B9EGA3 [Direct mapping] SMARCD2 protein; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016514 [SWI/SNF complex] GO:0043044 [ATP-dependent chromatin remodeling] Show all	494 aa 55.9 kDa	No	0