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Most normal tissues displayed moderate cytoplasmic positivity with a granular pattern. Strong immunoreactivity was observed in the gastrointestinal tract, islets of Langerhans, adrenal gland, prostate, trophoblasts and Purkinje cells. Heart and skeletal muscle was negative.
CAB013676
A majority of malignancies showed weak to moderate cytoplasmic staining. The gastrointestinal tract and trophoblastic cells in placenta were strongly stained. Liver, cells in CNS, lymphoid tissues and myocytes were generally negative.