Cell atlas - ABI3 - The Human Protein Atlas

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ABI3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ABI3
Gene description	ABI family, member 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (HUVEC TERT2, TIME, Daudi, HDLM-2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HUVEC TERT2, TIME, Daudi, HDLM-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ABI3 (HGNC Symbol)
Synonyms	NESH, SSH3BP3
Description	ABI family, member 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Chromosome	17
Cytoband	q21.32
Chromosome location (bp)	49210227 - 49223225
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108798 (version 83.38)
Entrez gene	51225
UniProt	Q9P2A4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P2A4
Antibodypedia	ABI3 antibodies

PROTEIN BROWSER

ABI3-001	ABI3-002	ABI3-003	ABI3-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABI3-001 ENSP00000225941 ENST00000225941	Q9P2A4 [Direct mapping] ABI gene family member 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0006928 [movement of cell or subcellular component] GO:0016020 [membrane] GO:0030027 [lamellipodium] GO:0030334 [regulation of cell migration] Show all	366 aa 39 kDa	No	0
ABI3-002 ENSP00000406651 ENST00000419580	Q9P2A4 [Direct mapping] ABI gene family member 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0006928 [movement of cell or subcellular component] GO:0016020 [membrane] GO:0030027 [lamellipodium] GO:0030334 [regulation of cell migration] Show all	360 aa 38.4 kDa	No	0
ABI3-003 ENSP00000460776 ENST00000573347	I3L3W4 [Direct mapping] ABI gene family member 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		160 aa 16.1 kDa	No	0
ABI3-004 ENSP00000459171 ENST00000571035	I3L1X2 [Direct mapping] ABI gene family member 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	191 aa 19.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.