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Enzymes ENZYME proteins Oxidoreductases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0004052 [arachidonate 12-lipoxygenase activity] GO:0005506 [iron ion binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006928 [movement of cell or subcellular component] GO:0007568 [aging] GO:0008284 [positive regulation of cell proliferation] GO:0010595 [positive regulation of endothelial cell migration] GO:0010628 [positive regulation of gene expression] GO:0010656 [negative regulation of muscle cell apoptotic process] GO:0010942 [positive regulation of cell death] GO:0016020 [membrane] GO:0016165 [linoleate 13S-lipoxygenase activity] GO:0016702 [oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen] GO:0019369 [arachidonic acid metabolic process] GO:0019372 [lipoxygenase pathway] GO:0019395 [fatty acid oxidation] GO:0030307 [positive regulation of cell growth] GO:0030335 [positive regulation of cell migration] GO:0042383 [sarcolemma] GO:0042554 [superoxide anion generation] GO:0043065 [positive regulation of apoptotic process] GO:0043066 [negative regulation of apoptotic process] GO:0043280 [positive regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0043651 [linoleic acid metabolic process] GO:0044281 [small molecule metabolic process] GO:0045603 [positive regulation of endothelial cell differentiation] GO:0045766 [positive regulation of angiogenesis] GO:0045785 [positive regulation of cell adhesion] GO:0045909 [positive regulation of vasodilation] GO:0046872 [metal ion binding] GO:0047977 [hepoxilin-epoxide hydrolase activity] GO:0048661 [positive regulation of smooth muscle cell proliferation] GO:0051120 [hepoxilin A3 synthase activity] GO:0051121 [hepoxilin metabolic process] GO:0051122 [hepoxilin biosynthetic process] GO:0051901 [positive regulation of mitochondrial depolarization] GO:0055114 [oxidation-reduction process] GO:0061436 [establishment of skin barrier] GO:0070062 [extracellular exosome] GO:0071396 [cellular response to lipid] GO:0072593 [reactive oxygen species metabolic process] GO:0090331 [negative regulation of platelet aggregation] GO:1901751 [leukotriene A4 metabolic process] GO:2001300 [lipoxin metabolic process] GO:2001303 [lipoxin A4 biosynthetic process] GO:2001306 [lipoxin B4 biosynthetic process]
Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0005506 [iron ion binding] GO:0016702 [oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process]