Expression of CWH43 in cancer - Summary - The Human Protein Atlas

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CWH43

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CWH43
Gene description	Cell wall biogenesis 43 C-terminal homolog
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (prostate cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enhanced (prostate)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA042814 , HPA048140
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and endometrial cancer (favourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042814	HPA048140

GENE INFORMATION
Gene name	CWH43 (HGNC Symbol)
Synonyms	CWH43-C, FLJ21511
Description	Cell wall biogenesis 43 C-terminal homolog (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p11
Chromosome location (bp)	48986247 - 49062081
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109182 (version 83.38)
Entrez gene	80157
UniProt	Q9H720 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H720
Antibodypedia	CWH43 antibodies

PROTEIN BROWSER

CWH43-001	CWH43-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CWH43-001 ENSP00000226432 ENST00000226432	Q9H720 [Direct mapping] PGAP2-interacting protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006506 [GPI anchor biosynthetic process] GO:0016021 [integral component of membrane] Show all	699 aa 78.6 kDa	No	>9
CWH43-002 ENSP00000422802 ENST00000513409	E7EQL2 [Direct mapping] PGAP2-interacting protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	672 aa 75.5 kDa	No	>9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.