Cell atlas - BST1 - The Human Protein Atlas

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BST1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	BST1
Gene description	Bone marrow stromal cell antigen 1
Protein class	CD markers Enzymes Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (THP-1, WM-115, U-937, TIME)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (THP-1, WM-115, U-937, TIME) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	BST1 (HGNC Symbol)
Synonyms	CD157
Description	Bone marrow stromal cell antigen 1 (HGNC Symbol)
Entrez gene summary	Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	p15.32
Chromosome location (bp)	15702950 - 15738313
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109743 (version 83.38)
Entrez gene	683
UniProt	Q10588 (UniProt - Evidence at protein level)
neXtProt	NX_Q10588
Antibodypedia	BST1 antibodies

PROTEIN BROWSER

BST1-001	BST1-002	BST1-003	BST1-004	BST1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BST1-001 ENSP00000265016 ENST00000265016	Q10588 [Direct mapping] ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Show all	Enzymes ENZYME proteins Hydrolases CD markers MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003953 [NAD+ nucleosidase activity] GO:0005886 [plasma membrane] GO:0006959 [humoral immune response] GO:0007275 [multicellular organismal development] GO:0008152 [metabolic process] GO:0016740 [transferase activity] GO:0016849 [phosphorus-oxygen lyase activity] GO:0019898 [extrinsic component of membrane] GO:0030890 [positive regulation of B cell proliferation] GO:0031225 [anchored component of membrane] GO:0050135 [NAD(P)+ nucleosidase activity] GO:0070062 [extracellular exosome] Show all	318 aa 35.7 kDa	Yes	0
BST1-002 ENSP00000371783 ENST00000382346	A6NC48 [Direct mapping] ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003953 [NAD+ nucleosidase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0016849 [phosphorus-oxygen lyase activity] GO:0030890 [positive regulation of B cell proliferation] Show all	333 aa 37.5 kDa	Yes	0
BST1-003 ENSP00000424761 ENST00000514989	H0Y9Q9 [Direct mapping] ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003953 [NAD+ nucleosidase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0016849 [phosphorus-oxygen lyase activity] GO:0030890 [positive regulation of B cell proliferation] Show all	97 aa 11 kDa	No	0
BST1-004 ENSP00000423357 ENST00000505785	H0Y984 [Direct mapping] ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003953 [NAD+ nucleosidase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0016849 [phosphorus-oxygen lyase activity] GO:0030890 [positive regulation of B cell proliferation] Show all	186 aa 21 kDa	No	0
BST1-005 ENSP00000420925 ENST00000514445	H0Y8G4 [Direct mapping] ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003953 [NAD+ nucleosidase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0016849 [phosphorus-oxygen lyase activity] GO:0030890 [positive regulation of B cell proliferation] Show all	155 aa 17.6 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.