Tissue expression of ACAD10 - Summary - The Human Protein Atlas

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ACAD10

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ACAD10
Gene description	Acyl-CoA dehydrogenase family, member 10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA067222
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ACAD10 (HGNC Symbol)
Synonyms	MGC5601
Description	Acyl-CoA dehydrogenase family, member 10 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]
Chromosome	12
Cytoband	q24.12
Chromosome location (bp)	111686056 - 111757107
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000111271 (version 83.38)
Entrez gene	80724
UniProt	Q6JQN1 (UniProt - Evidence at protein level)
neXtProt	NX_Q6JQN1
Antibodypedia	ACAD10 antibodies

PROTEIN BROWSER

ACAD10-001	ACAD10-002	ACAD10-007	ACAD10-009	ACAD10-010	ACAD10-014	ACAD10-018	ACAD10-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACAD10-001 ENSP00000325137 ENST00000313698	Q6JQN1 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0003995 [acyl-CoA dehydrogenase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006635 [fatty acid beta-oxidation] GO:0008152 [metabolic process] GO:0009055 [electron carrier activity] GO:0016627 [oxidoreductase activity, acting on the CH-CH group of donors] GO:0016787 [hydrolase activity] GO:0033539 [fatty acid beta-oxidation using acyl-CoA dehydrogenase] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0050660 [flavin adenine dinucleotide binding] GO:0052890 [oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor] GO:0055088 [lipid homeostasis] GO:0055114 [oxidation-reduction process] Show all	1059 aa 118.8 kDa	No	0
ACAD10-002 ENSP00000389813 ENST00000455480	Q6JQN1 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000062 [fatty-acyl-CoA binding] GO:0003995 [acyl-CoA dehydrogenase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006635 [fatty acid beta-oxidation] GO:0008152 [metabolic process] GO:0009055 [electron carrier activity] GO:0016627 [oxidoreductase activity, acting on the CH-CH group of donors] GO:0016787 [hydrolase activity] GO:0033539 [fatty acid beta-oxidation using acyl-CoA dehydrogenase] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0050660 [flavin adenine dinucleotide binding] GO:0052890 [oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor] GO:0055088 [lipid homeostasis] GO:0055114 [oxidation-reduction process] Show all	1090 aa 122.3 kDa	No	0
ACAD10-007 ENSP00000447561 ENST00000552706	F8W0Q4 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		226 aa 25.2 kDa	No	0
ACAD10-009 ENSP00000421527 ENST00000514615	D6RFF6 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		96 aa 11.1 kDa	No	0
ACAD10-010 ENSP00000449097 ENST00000515283	F8VXK4 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016627 [oxidoreductase activity, acting on the CH-CH group of donors] GO:0050660 [flavin adenine dinucleotide binding] GO:0055114 [oxidation-reduction process] Show all	146 aa 16.4 kDa	No	0
ACAD10-014 ENSP00000446711 ENST00000507683	F8W179 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		278 aa 31 kDa	No	0
ACAD10-018 ENSP00000446959 ENST00000549590	F8W1I9 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	710 aa 80.5 kDa	No	0
ACAD10-019 ENSP00000446998 ENST00000552965	F8W1A9 [Direct mapping] Acyl-CoA dehydrogenase family member 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		13 aa 1.6 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.