Fields »
ABOUT
HELP
BLOG
BVES

GENERAL INFORMATION

Gene name

 BVES

Gene description

 Blood vessel epicardial substance

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (smooth muscle)
GTEx:Tissue enhanced (skeletal muscle)
FANTOM5:Tissue enhanced (skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 Distinct membranous expression in cardiac myocytes with additional cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA014788 , HPA018176
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (smooth muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skeletal muscle)

GENE INFORMATION

Gene name

 BVES (HGNC Symbol)

Synonyms

 HBVES, POP1, POPDC1

Description

 Blood vessel epicardial substance (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

Chromosome

 6

Cytoband

 q21

Chromosome location (bp)

 105096822 - 105137174

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112276 (version 83.38)

Entrez gene

 11149

UniProt

 Q8NE79 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NE79

Antibodypedia

 BVES antibodies

PROTEIN BROWSER
BVES-001
BVES-002
BVES-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BVES-001
ENSP00000337259
ENST00000336775
Q8NE79 [Direct mapping]
Blood vessel epicardial substance
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001921 [positive regulation of receptor recycling]
GO:0005198 [structural molecule activity]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007517 [muscle organ development]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016328 [lateral plasma membrane]
GO:0034446 [substrate adhesion-dependent cell spreading]
GO:0040017 [positive regulation of locomotion]
GO:0043087 [regulation of GTPase activity]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 360 aa
41.5 kDa 		No 2
BVES-002
ENSP00000397310
ENST00000446408
Q8NE79 [Direct mapping]
Blood vessel epicardial substance
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001921 [positive regulation of receptor recycling]
GO:0005198 [structural molecule activity]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007517 [muscle organ development]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016328 [lateral plasma membrane]
GO:0034446 [substrate adhesion-dependent cell spreading]
GO:0040017 [positive regulation of locomotion]
GO:0043087 [regulation of GTPase activity]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 360 aa
41.5 kDa 		No 3
BVES-003
ENSP00000313172
ENST00000314641
Q8NE79 [Direct mapping]
Blood vessel epicardial substance
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001921 [positive regulation of receptor recycling]
GO:0002027 [regulation of heart rate]
GO:0002244 [hematopoietic progenitor cell differentiation]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007517 [muscle organ development]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0016328 [lateral plasma membrane]
GO:0030552 [cAMP binding]
GO:0031253 [cell projection membrane]
GO:0034446 [substrate adhesion-dependent cell spreading]
GO:0040017 [positive regulation of locomotion]
GO:0042391 [regulation of membrane potential]
GO:0043087 [regulation of GTPase activity]
GO:0048278 [vesicle docking]
GO:0060931 [sinoatrial node cell development]
GO:0060973 [cell migration involved in heart development]
GO:0090136 [epithelial cell-cell adhesion]
GO:2001135 [regulation of endocytic recycling]
Show all
 360 aa
41.5 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.