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CEP72

GENERAL INFORMATION

Gene name

 CEP72

Gene description

 Centrosomal protein 72kDa

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (HDLM-2)
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Mainly nucleolar expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA058235
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable).
Endometrial cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA058235

GENE INFORMATION

Gene name

 CEP72 (HGNC Symbol)

Synonyms

 FLJ10565, KIAA1519

Description

 Centrosomal protein 72kDa (HGNC Symbol)

Entrez gene summary

 The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 p15.33

Chromosome location (bp)

 612272 - 667168

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112877 (version 83.38)

Entrez gene

 55722

UniProt

 Q9P209 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9P209

Antibodypedia

 CEP72 antibodies

PROTEIN BROWSER
CEP72-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CEP72-001
ENSP00000264935
ENST00000264935
Q9P209 [Direct mapping]
Centrosomal protein of 72 kDa
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0005515 [protein binding]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0006996 [organelle organization]
GO:0007051 [spindle organization]
GO:0033566 [gamma-tubulin complex localization]
GO:0042802 [identical protein binding]
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 647 aa
71.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.