Cell atlas - SLC27A6 - The Human Protein Atlas

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SLC27A6

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear bodies

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SLC27A6
Gene description	Solute carrier family 27 (fatty acid transporter), member 6
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear bodies.
RNA cell category	Cell line enriched (BEWO)
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear bodies (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA008987
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (BEWO) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear bodies.

Main location

Nuclear bodies (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA008987	MCF7	Nuclear bodies	Intensity
	HPA008987	SH-SY5Y	Nuclear bodies

GENE INFORMATION
Gene name	SLC27A6 (HGNC Symbol)
Synonyms	ACSVL2, FACVL2, FATP6, VLCS-H1
Description	Solute carrier family 27 (fatty acid transporter), member 6 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q23.3
Chromosome location (bp)	128538013 - 129033642
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113396 (version 83.38)
Entrez gene	28965
UniProt	Q9Y2P4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y2P4
Antibodypedia	SLC27A6 antibodies

PROTEIN BROWSER

SLC27A6-001	SLC27A6-002	SLC27A6-003	SLC27A6-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC27A6-001 ENSP00000262462 ENST00000262462	Q9Y2P4 [Direct mapping] Long-chain fatty acid transport protein 6 Show all	Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000038 [very long-chain fatty acid metabolic process] GO:0000166 [nucleotide binding] GO:0001676 [long-chain fatty acid metabolic process] GO:0003824 [catalytic activity] GO:0004467 [long-chain fatty acid-CoA ligase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015909 [long-chain fatty acid transport] GO:0016021 [integral component of membrane] GO:0031957 [very long-chain fatty acid-CoA ligase activity] GO:0042383 [sarcolemma] GO:0055085 [transmembrane transport] Show all	619 aa 70.1 kDa	No	2
SLC27A6-002 ENSP00000421759 ENST00000508645	D6RAJ2 [Direct mapping] Long-chain fatty acid transport protein 6 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001676 [long-chain fatty acid metabolic process] GO:0003824 [catalytic activity] GO:0004467 [long-chain fatty acid-CoA ligase activity] GO:0008152 [metabolic process] GO:0015908 [fatty acid transport] GO:0016021 [integral component of membrane] GO:0031957 [very long-chain fatty acid-CoA ligase activity] Show all	162 aa 17.7 kDa	No	0
SLC27A6-003 ENSP00000378684 ENST00000395266	Q9Y2P4 [Direct mapping] Long-chain fatty acid transport protein 6 Show all	Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000038 [very long-chain fatty acid metabolic process] GO:0000166 [nucleotide binding] GO:0001676 [long-chain fatty acid metabolic process] GO:0003824 [catalytic activity] GO:0004467 [long-chain fatty acid-CoA ligase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015909 [long-chain fatty acid transport] GO:0016021 [integral component of membrane] GO:0042383 [sarcolemma] GO:0055085 [transmembrane transport] Show all	619 aa 70.1 kDa	No	2
SLC27A6-004 ENSP00000421024 ENST00000506176	Q9Y2P4 [Direct mapping] Long-chain fatty acid transport protein 6 Show all	Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000038 [very long-chain fatty acid metabolic process] GO:0000166 [nucleotide binding] GO:0001676 [long-chain fatty acid metabolic process] GO:0003824 [catalytic activity] GO:0004467 [long-chain fatty acid-CoA ligase activity] GO:0005886 [plasma membrane] GO:0008152 [metabolic process] GO:0015909 [long-chain fatty acid transport] GO:0016021 [integral component of membrane] GO:0042383 [sarcolemma] GO:0055085 [transmembrane transport] Show all	619 aa 70.1 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.