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CDX1

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GENERAL INFORMATION

Gene name

 CDX1

Gene description

 Caudal type homeobox 1

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Group enriched (BJ hTERT+, SH-SY5Y)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (BJ hTERT+, SH-SY5Y)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 CDX1

Synonyms

Description

 Caudal type homeobox 1 (HGNC Symbol)

Entrez gene summary

 This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 150166795 - 150184558

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000113722 (version 83.38)

Entrez gene

 1044

UniProt

 P47902 (UniProt - Evidence at protein level)

neXtProt

 NX_P47902

Antibodypedia

 CDX1 antibodies

PROTEIN BROWSER
CDX1-001
CDX1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CDX1-001
ENSP00000231656
ENST00000231656
P47902 [Direct mapping]
Homeobox protein CDX-1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Show all
GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding]
GO:0001205 [transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0007389 [pattern specification process]
GO:0009887 [organ morphogenesis]
GO:0009948 [anterior/posterior axis specification]
GO:0009952 [anterior/posterior pattern specification]
GO:0014807 [regulation of somitogenesis]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0060349 [bone morphogenesis]
Show all
 265 aa
28.1 kDa 		No 0
CDX1-201
ENSP00000477928
ENST00000616154
A0A087WTJ6 [Direct mapping]
Homeobox protein CDX-1
Show all
Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 154 aa
17.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.