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Cancer tissues showed cytoplasmic and moderate positivity.
GENE INFORMATION
Gene name
BCHE (HGNC Symbol)
Synonyms
CHE1, CHE2, E1
Description
Butyrylcholinesterase (HGNC Symbol)
Entrez gene summary
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]