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EIF4G1

GENERAL INFORMATION

Gene name

 EIF4G1

Gene description

 Eukaryotic translation initiation factor 4 gamma, 1

Protein class

 Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 27
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Mainly cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA028487 , CAB014774
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 EIF4G1 (HGNC Symbol)

Synonyms

 EIF4F, EIF4G, p220, PARK18

Description

 Eukaryotic translation initiation factor 4 gamma, 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]

Chromosome

 3

Cytoband

 q27.1

Chromosome location (bp)

 184314495 - 184335358

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000114867 (version 83.38)

Entrez gene

 1981

UniProt

 Q04637 (UniProt - Evidence at protein level)

neXtProt

 NX_Q04637

Antibodypedia

 EIF4G1 antibodies

PROTEIN BROWSER
«
EIF4G1-001
EIF4G1-003
EIF4G1-005
EIF4G1-006
EIF4G1-007
EIF4G1-008
EIF4G1-009
EIF4G1-010
EIF4G1-012
EIF4G1-013
EIF4G1-014
EIF4G1-015
EIF4G1-016
EIF4G1-020
EIF4G1-022
EIF4G1-023
EIF4G1-024
EIF4G1-027
EIF4G1-028
EIF4G1-029
EIF4G1-031
EIF4G1-037
EIF4G1-038
EIF4G1-039
EIF4G1-041
EIF4G1-201
EIF4G1-202
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EIF4G1-001
ENSP00000343450
ENST00000342981
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1600 aa
175.6 kDa 		No 0
EIF4G1-003
ENSP00000376320
ENST00000392537
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1512 aa
166.6 kDa 		No 0
EIF4G1-005
ENSP00000403269
ENST00000426123
C9JF13 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 903 aa
98.2 kDa 		No 0
EIF4G1-006
ENSP00000413159
ENST00000421110
C9K073 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 869 aa
93.4 kDa 		No 0
EIF4G1-007
ENSP00000316879
ENST00000346169
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1599 aa
175.5 kDa 		No 0
EIF4G1-008
ENSP00000391412
ENST00000450424
C9J2Z7 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 834 aa
89.2 kDa 		No 0
EIF4G1-009
ENSP00000317600
ENST00000350481
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1435 aa
158.5 kDa 		No 0
EIF4G1-010
ENSP00000391935
ENST00000414031
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1559 aa
171.5 kDa 		No 0
EIF4G1-012
ENSP00000407682
ENST00000427845
E9PGM1 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008190 [eukaryotic initiation factor 4E binding]
Show all
 1513 aa
166.7 kDa 		No 0
EIF4G1-013
ENSP00000416255
ENST00000424196
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0001662 [behavioral fear response]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0045666 [positive regulation of neuron differentiation]
Show all
 1606 aa
176.2 kDa 		No 0
EIF4G1-014
ENSP00000371767
ENST00000382330
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1606 aa
176.2 kDa 		No 0
EIF4G1-015
ENSP00000398145
ENST00000444861
C9J6B6 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 757 aa
82.5 kDa 		No 0
EIF4G1-016
ENSP00000411826
ENST00000434061
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1404 aa
154.9 kDa 		No 0
EIF4G1-020
ENSP00000415842
ENST00000455679
C9JIH5 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 87 aa
9.2 kDa 		No 0
EIF4G1-022
ENSP00000407240
ENST00000440448
C9JWH9 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 144 aa
14.9 kDa 		No 0
EIF4G1-023
ENSP00000411214
ENST00000427141
C9J987 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 92 aa
9.9 kDa 		No 0
EIF4G1-024
ENSP00000415943
ENST00000456033
C9JHW9 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 160 aa
17 kDa 		No 0
EIF4G1-027
ENSP00000411707
ENST00000428387
C9J556 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 143 aa
14.8 kDa 		No 0
EIF4G1-028
ENSP00000409545
ENST00000427607
C9JSU8 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 163 aa
16.9 kDa 		No 0
EIF4G1-029
ENSP00000399969
ENST00000457456
C9JWW9 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 285 aa
29.3 kDa 		No 0
EIF4G1-031
ENSP00000392908
ENST00000448284
H7C044 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 226 aa
24.7 kDa 		No 0
EIF4G1-037
ENSP00000407244
ENST00000444134
C9JWH7 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 127 aa
13 kDa 		No 0
EIF4G1-038
ENSP00000395974
ENST00000411531
E7EUU4 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008190 [eukaryotic initiation factor 4E binding]
Show all
 1560 aa
171.6 kDa 		No 0
EIF4G1-039
ENSP00000399858
ENST00000441154
E7EX73 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 1436 aa
158.6 kDa 		No 0
EIF4G1-041
ENSP00000404754
ENST00000435046
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1403 aa
154.8 kDa 		No 0
EIF4G1-201
ENSP00000323737
ENST00000319274
A0A0A0MR52 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005488 [binding]
GO:0005515 [protein binding]
Show all
 1395 aa
153.2 kDa 		No 0
EIF4G1-202
ENSP00000338020
ENST00000352767
Q04637 [Direct mapping]
Eukaryotic translation initiation factor 4 gamma 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening]
GO:0003723 [RNA binding]
GO:0003743 [translation initiation factor activity]
GO:0005488 [binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008190 [eukaryotic initiation factor 4E binding]
GO:0008286 [insulin receptor signaling pathway]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016281 [eukaryotic translation initiation factor 4F complex]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0043488 [regulation of mRNA stability]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1606 aa
176.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.